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LIME1 and AGR3
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
LIME1
AGR3
Description
Lck interacting transmembrane adaptor 1
anterior gradient 3, protein disulphide isomerase family member
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
Membrane
B Cell Receptor Complex
Endoplasmic Reticulum
Molecular Function
Protein Binding
Protein Kinase Binding
Dystroglycan Binding
Protein Binding
Biological Process
Adaptive Immune Response
Immune System Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Canonical NF-kappaB Signal Transduction
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Asthma (
31619474
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Bell's palsy (
33602968
)
Crohn's disease (
28067908
)
Estimated glomerular filtration rate (
31015462
)
Inflammatory bowel disease (
23128233
28067908
)
Lipoprotein (a) levels (
33730874
)
Meat-related diet (
32066663
)
Prostate cancer (
23535732
)
Refractive error (
32231278
)
Ulcerative colitis (
28067908
)
Coffee consumption (
29367735
31959922
)
Cutaneous malignant melanoma (
26237428
32341527
)
Cutaneous squamous cell carcinoma (
32041948
)
Diffusing capacity of carbon monoxide (
30694715
)
Lung cancer in ever smokers (
28604730
)
Melanoma (
28212542
)
Refractive error (
32231278
)
Residual cognition (
28441426
)
Rosacea symptom severity (
29771307
)
Type 2 diabetes (dietary heme iron intake interaction) (
23386860
)
Urinary albumin excretion (
30220432
)
Urinary albumin excretion (no hypertensive medication) (
30220432
)
Interacting Genes
46 interacting genes:
AGR3
AIG1
AQP1
ARFGAP3
BNIP2
C14orf180
CALN1
CIAO2A
CLN6
EMD
FRMD8
GAD2
GOSR2
GRB2
LCK
LHFPL5
LPAR3
LYN
MAN2B2
MEST
MIEF2
NDRG4
NINJ1
PBX3
PKMYT1
PLCG2
PNPO
PTPN9
RTP2
SEC22C
SLC41A2
SNAP47
SNX1
STX6
STX7
TBRG4
TMBIM6
TMEM143
TMEM243
TMEM74
TMEM86B
TMEM97
TRAF3IP3
UNC93B1
UPK2
ZFPL1
35 interacting genes:
AKT1
AP1B1
APC
ASB10
BCAR3
CASP8
CATSPER1
CD46
CGRRF1
CNNM3
DAG1
DESI1
EDA2R
ERLIN1
ESR2
FXYD3
KRTAP11-1
LIME1
LSM1
LYPD3
MMGT1
NRM
NTAQ1
NUP62
PDZK1IP1
PRAF2
PTPN1
SGTA
SGTB
SPINT1
TGFB1
TIMMDC1
TMEM14B
UBQLN1
UBQLN2
Entrez ID
54923
155465
HPRD ID
07904
16545
Ensembl ID
ENSG00000203896
ENSG00000173467
Uniprot IDs
A0A087WT39
Q9H400
Q8TD06
PDB IDs
3PH9
Enriched GO Terms of Interacting Partners
?
Membrane
SNAP Receptor Activity
SNARE Complex
B Cell Receptor Signaling Pathway
Organelle Fusion
Lysosome
Ephrin Receptor Binding
Regulation Of Cellular Localization
Vesicle Organization
Plasma Membrane
Organelle Membrane Fusion
Vesicle Fusion
Protein Binding
Phosphotyrosine Residue Binding
T Cell Costimulation
Positive Regulation Of Immune Response
Immune Response-activating Signaling Pathway
Phosphorylation-dependent Protein Binding
Syntaxin Binding
Fc Receptor Signaling Pathway
Golgi Apparatus
Vesicle Docking
Spindle Pole Centrosome
Antigen Receptor-mediated Signaling Pathway
Endomembrane System
SNARE Binding
Immune Response-regulating Signaling Pathway
Membrane Fusion
Vesicle-mediated Transport
Activation Of Immune Response
Regulation Of Response To Endoplasmic Reticulum Stress
Positive Regulation Of Response To Endoplasmic Reticulum Stress
TRC Complex
Positive Regulation Of ERAD Pathway
Response To Endoplasmic Reticulum Stress
Regulation Of Proteolysis
Regulation Of ERAD Pathway
Insulin Receptor Signaling Pathway
Positive Regulation Of Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Glial Cell Differentiation
ERAD Pathway
Positive Regulation Of Protein Catabolic Process
Membrane
Positive Regulation Of Protein Localization To Centrosome
Positive Regulation Of Proteasomal Protein Catabolic Process
Response To Fluid Shear Stress
Regulation Of Protein Catabolic Process
Proteolysis
Negative Regulation Of Response To Endoplasmic Reticulum Stress
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Establishment Of Protein Localization
Cellular Response To Decreased Oxygen Levels
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Protein Catabolic Process
Negative Regulation Of PERK-mediated Unfolded Protein Response
Regulation Of Protein Localization To Centrosome
Cellular Response To Oxygen Levels
Positive Regulation Of Gliogenesis
Regulation Of Sodium Ion Transport
Regulation Of Glial Cell Differentiation
Vascular Endothelial Cell Response To Fluid Shear Stress
Regulation Of PERK-mediated Unfolded Protein Response
Positive Regulation Of Fibroblast Migration
Positive Regulation Of Macrophage Differentiation
Cellular Response To Mechanical Stimulus
Regulation Of Canonical NF-kappaB Signal Transduction
Tail-anchored Membrane Protein Insertion Into ER Membrane
Lamellipodium
Regulation Of Metal Ion Transport
Laminin Binding
Regulation Of Protein Metabolic Process
Establishment Of Protein Localization To Membrane
Response To Laminar Fluid Shear Stress
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Catabolic Process
Autophagosome Assembly
Positive Regulation Of Endothelial Cell Apoptotic Process
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Tagcloud (Intersection)
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