SYK and SH2B2

  • Number of citations of the paper that reports this interaction (PMID 10872802)
  • 9
  • Data Source:
  • HPRD (in vivo)

SYK

SH2B2

Gene Name spleen tyrosine kinase SH2B adaptor protein 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 98 interactors: APP BLNK BTK CALM1 CBL CBLB CD19 CD22 CD3E CD72 CD79A CD79B CRKL CSF2RB CSF3R CTTN DBNL DUSP3 EGFR EPOR ERBB2 ERBB3 ERBB4 FCER1G FCGR1A FCGR2A FCGR3A FCRL3 FGR FYN GAB2 GRB2 HCLS1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC6 HDAC9 HNRNPU IL15RA IL2RB ITGB2 JAK1 LAT LAX1 LCK LCP2 LYN MAP4K1 MAPK3 MAPT MS4A2 NEDD4 NFAM1 PAG1 PIK3AP1 PIK3R1 PIK3R2 PLCG1 PLCG2 POU2AF1 PRKCA PRKD1 PTK2 PTK2B PTPN6 PXN RASA1 RPS10 RPS6KA1 RPS6KB1 RPS6KB2 SELPLG SH2B2 SH2D2A SH3BP2 SHC1 SIT1 SLA SLC4A1 SNCA SRC STAT1 STAT3 STAT5A TERF1 TLR4 TNFRSF1A TRAF6 TUBA1A TUBA4A TYROBP UBASH3B UBB USP25 VAV1 VAV2 21 interactors: AKT1 ASB6 BTK CBL EPOR ERBB2 FYN GRB2 INSR JAK1 JAK2 JAK3 KIT LYN NTRK1 NTRK2 PDLIM7 SH2B1 SHC1 SORBS1 SYK
Entrez ID 6850 10603
HPRD ID 02514 16097
Ensembl ID ENSG00000165025
Uniprot IDs A8K4G2 P43405 O14492
PDB IDs 1A81 1CSY 1CSZ 1XBA 1XBB 1XBC 3BUW 3EMG 3FQE 3FQH 3FQS 3SRV 3TUB 3TUC 3TUD 3VF8 3VF9 4DFL 4DFN 4F4P 4FL1 4FL2 4FL3 4FYN 4FYO 4FZ6 4FZ7 4GFG 1Q2H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
belongs  bind  binds  blotting  coimmunoprecipitation  contribution  cytokine  domains  epo  epor  erythroid  erythropoietin  far  homology  individually  interaction  jak2  mediate  paper  participated  propose  recombinant  regulates  sh2  src  tandem  tyrosine  tyrosines  ut7 
accordingly  adaptor  aps  assembling  called  counteract  dephosphorylation  dimerization  dimers  hetero  homo  hyperphagia  insects  irs1  irs2  leptin  obesity  protecting  protects  psm  sh2b1  sh2b1beta  sh2b3  transgenes  trka  tyrosyl 
Tagcloud (Difference) ?
belongs  bind  binds  blotting  coimmunoprecipitation  contribution  cytokine  domains  epo  epor  erythroid  erythropoietin  far  homology  individually  interaction  jak2  mediate  paper  participated  propose  recombinant  regulates  src  tandem  tyrosine  tyrosines  ut7 
accordingly  adaptor  aps  assembling  called  counteract  dephosphorylation  dimerization  dimers  hetero  homo  hyperphagia  insects  irs1  irs2  leptin  obesity  protecting  protects  psm  sh2b1  sh2b1beta  sh2b3  transgenes  trka  tyrosyl 
Tagcloud (Intersection) ?
sh2