Wiki-Pi
About
Search
People
Updates
Search
LCE1F and FBLN1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
LCE1F
FBLN1
Description
late cornified envelope 1F
fibulin 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Basement Membrane
Extracellular Space
Extracellular Matrix
Extracellular Exosome
Elastic Fiber
Molecular Function
Protein Binding
Identical Protein Binding
Fibronectin Binding
Integrin Binding
Extracellular Matrix Structural Constituent
Calcium Ion Binding
Protein Binding
Peptidase Activator Activity
Identical Protein Binding
Protein-containing Complex Binding
Fibrinogen Binding
Biological Process
Epidermis Development
Keratinization
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Cell Adhesion
Integrin-mediated Signaling Pathway
Embryo Implantation
Positive Regulation Of Gene Expression
Extracellular Matrix Organization
Positive Regulation Of Fibroblast Proliferation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Transforming Growth Factor Beta Production
Blood Coagulation, Fibrin Clot Formation
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Transformation Of Host Cell By Virus
Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate
Negative Regulation Of Cell Motility
Negative Regulation Of Stem Cell Proliferation
Pathways
Formation of the cornified envelope
Molecules associated with elastic fibres
Molecules associated with elastic fibres
Drugs
Diseases
Synpolydactyly, 3/3'4, associated with metacarpal and metatarsal synostoses
GWAS
Asthma (
31619474
)
Blood protein levels (
30072576
)
Colon cancer (
33632709
)
Distal colorectal cancer (
33632709
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Low density lipoprotein cholesterol levels (
32154731
)
Paneth cell defects in Crohn's disease (
28352666
)
Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) (
33987465
)
QT interval (
29213071
)
Red blood cell count (
27863252
)
Temperament (bipolar disorder) (
22365631
)
Interacting Genes
90 interacting genes:
ADAMTSL4
ALPP
CATSPER1
CHIC2
CHRD
CRCT1
CREB5
CYP21A2
CYSRT1
FBLN1
HOXA1
IL34
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-5
KRTAP10-6
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP2-3
KRTAP2-4
KRTAP3-2
KRTAP3-3
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE2A
LCE2B
LCE2C
LCE2D
LCE3B
LCE3C
LCE4A
LCE5A
MACO1
MDFI
NBPF19
NECTIN2
NOTCH2NLA
NTAQ1
NUFIP2
OIT3
OTX1
PCSK5
PLA2G10
POU4F2
PSMB1
RAD54L2
RGS17
RGS20
RNF4
SLC39A7
SMCP
SPRY1
SPRY2
SPRY3
TGFB1
TRIM42
UBE2I
VASN
VWC2
WFDC3
66 interacting genes:
ACAN
ADAMTSL2
ADAMTSL4
AK3
ALG10
APOA1
APP
ATN1
BHLHE40
CACNA1A
CCN2
CCN3
CHIC2
CREB5
CRIPTO
CXCL5
DDIAS
ECM1
EDC4
ELN
FGB
FN1
FXR1
GFI1B
HBEGF
HOXA1
HSPG2
ITGB1
KLHL20
KRTAP11-1
KRTAP19-2
LCE1A
LCE1B
LCE1C
LCE1D
LCE1F
LCE3A
LCE5A
LINGO1
LMNTD2
LTBP4
MCPH1
MEOX2
MFAP5
MOB4
MRPL12
NEDD1
NID1
NLGN3
NOTCH3
NUFIP2
PAX5
PLSCR1
PPARA
SKIL
SLC66A2
SMAD3
SMAD4
SPRY1
TAF9
TANK
TCF7L2
TRIM42
UNKL
VCAN
YWHAQ
Entrez ID
353137
2192
HPRD ID
13970
00629
Ensembl ID
ENSG00000240386
ENSG00000077942
Uniprot IDs
Q5T754
A0A8S0LWY1
P23142
Q8NBH6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Intermediate Filament
Keratin Filament
Keratinization
Epidermis Development
Tissue Development
Hair Cycle
Protein Binding
Identical Protein Binding
Branch Elongation Of An Epithelium
Axis Elongation
Cytosol
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Lens Fiber Cell Differentiation
Negative Regulation Of Ras Protein Signal Transduction
Microtubule End
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Bud Elongation Involved In Lung Branching
Interstitial Matrix
Extracellular Matrix
Tissue Development
Epidermis Development
Keratinization
Extracellular Matrix Structural Constituent
Developmental Process
Integrin Binding
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of MiRNA Transcription
Regulation Of Signal Transduction
Response To Interleukin-1
Extracellular Matrix Structural Constituent Conferring Compression Resistance
Regulation Of Intracellular Signal Transduction
Developmental Growth
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Endothelial Cell Migration
Negative Regulation Of Signal Transduction
Regulation Of MiRNA Metabolic Process
Angiogenesis
Regulation Of Cell Communication
Regulation Of Signaling
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Extracellular Matrix Organization
Extracellular Structure Organization
Cell-matrix Adhesion
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of System Process
Anatomical Structure Formation Involved In Morphogenesis
Protein Binding
Negative Regulation Of Transcription By RNA Polymerase II
Animal Organ Development
Calcium-independent Cell-matrix Adhesion
Embryonic Pattern Specification
Adrenal Gland Development
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Identical Protein Binding
Extracellular Region
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Collagen Binding
Positive Regulation Of Cell-substrate Adhesion
Negative Regulation Of MiRNA Transcription
Cell Migration
Regulation Of Spontaneous Synaptic Transmission
Activin Receptor Signaling Pathway
Negative Regulation Of Macromolecule Metabolic Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?