LCE1F and OIT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCE1F	OIT3
Description		late cornified envelope 1F	oncoprotein induced transcript 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Space Nucleus Nuclear Envelope Cell Surface
	Molecular Function	Protein Binding Identical Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Epidermis Development Keratinization	Renal System Process
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31619474)	Coronary artery disease ( 33020668) Low density lipoprotein cholesterol levels ( 29403010 33339817) Refractive error ( 32231278) Total cholesterol levels ( 29403010 33339817)
Interacting Genes		90 interacting genes: ADAMTSL4 ALPP CATSPER1 CHIC2 CHRD CRCT1 CREB5 CYP21A2 CYSRT1 FBLN1 HOXA1 IL34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A LCE5A MACO1 MDFI NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 OIT3 OTX1 PCSK5 PLA2G10 POU4F2 PSMB1 RAD54L2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRY1 SPRY2 SPRY3 TGFB1 TRIM42 UBE2I VASN VWC2 WFDC3	9 interacting genes: CRCT1 FBXO34 HOXA1 KRTAP11-1 LCE1C LCE1F LCE3A MEOX2 VAC14
Entrez ID		353137	170392
HPRD ID		13970	17660
Ensembl ID		ENSG00000240386	ENSG00000138315
Uniprot IDs		Q5T754	Q8WWZ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Protein Binding Identical Protein Binding Branch Elongation Of An Epithelium Axis Elongation Cytosol Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Ras Protein Signal Transduction Microtubule End Negative Regulation Of Cellular Response To Growth Factor Stimulus Bud Elongation Involved In Lung Branching Interstitial Matrix	Keratinization Epidermis Development
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