LCE1F and MACO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCE1F	MACO1
Description		late cornified envelope 1F	macoilin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Endoplasmic Reticulum Membrane Axon Rough Endoplasmic Reticulum Membrane Nuclear Membrane Cell Projection Neuron Projection Neuron Projection Terminus Synapse
	Molecular Function	Protein Binding Identical Protein Binding	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Epidermis Development Keratinization	Chemotaxis Brain Development Neuronal Signal Transduction
Pathways		Formation of the cornified envelope	RHOA GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Asthma ( 31619474)	LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
Interacting Genes		90 interacting genes: ADAMTSL4 ALPP CATSPER1 CHIC2 CHRD CRCT1 CREB5 CYP21A2 CYSRT1 FBLN1 HOXA1 IL34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A LCE5A MACO1 MDFI NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 OIT3 OTX1 PCSK5 PLA2G10 POU4F2 PSMB1 RAD54L2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRY1 SPRY2 SPRY3 TGFB1 TRIM42 UBE2I VASN VWC2 WFDC3	26 interacting genes: CRCT1 HOXA1 KRTAP5-2 KRTAP5-7 LCE1A LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3D LCE3E LCE5A LINGO1 MEI4 MEOX2 NBPF19 NOTCH2NLA NR4A3 POTEB3 SMAD9 SMCP SRPK2 TMEM190 ZNF655
Entrez ID		353137	55219
HPRD ID		13970	13340
Ensembl ID		ENSG00000240386	ENSG00000204178
Uniprot IDs		Q5T754	Q8N5G2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Protein Binding Identical Protein Binding Branch Elongation Of An Epithelium Axis Elongation Cytosol Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Ras Protein Signal Transduction Microtubule End Negative Regulation Of Cellular Response To Growth Factor Stimulus Bud Elongation Involved In Lung Branching Interstitial Matrix	Keratinization Epidermis Development Tissue Development Developmental Process
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