IDH3A and RAB4A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		IDH3A	RAB4A
Gene Name		isocitrate dehydrogenase 3 (NAD+) alpha	RAB4A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix	Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity NAD Binding	GTPase Activity Protein Binding GTP Binding Protein Transporter Activity GDP Binding
	Biological Process	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Cellular Metabolic Process Small Molecule Metabolic Process	Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Membrane Organization
Pathways		Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)	Translocation of GLUT4 to the plasma membrane
Drugs		NADH
Diseases
GWAS			Aging ( 22773346)
Protein-Protein Interactions		5 interactors: IDH3B IDH3G MBNL1 RAB4A SUMO4	31 interactors: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830
Entrez ID		3419	5867
HPRD ID		03094	01541
Ensembl ID			ENSG00000168118
Uniprot IDs		B4DJB4 B7Z9J8 H0YL72 P50213	P20338
PDB IDs			1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?		Isocitrate Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Aerobic Respiration Cellular Respiration Energy Derivation By Oxidation Of Organic Compounds Alternative MRNA Splicing, Via Spliceosome Generation Of Precursor Metabolites And Energy 2-oxoglutarate Metabolic Process NADH Metabolic Process	Membrane Organization Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Cell Cycle Transport Regulation Of Catalytic Activity Regulation Of Cellular Localization Organelle Organization Ras Protein Signal Transduction Positive Regulation Of Catalytic Activity Protein Targeting Endocytosis Mitotic Cell Cycle Process Response To Wounding Membrane Fusion Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Regulation Of Protein Localization Mitotic Nuclear Division Intracellular Transport Regulation Of Cellular Component Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Intracellular Protein Transport Organelle Fusion Regulation Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Blood Coagulation Cellular Protein Localization Hemostasis Regulation Of Intracellular Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Hydrolase Activity Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Membrane Docking Mitotic DNA Damage Checkpoint Positive Regulation Of Transport Regulation Of Signal Transduction Intracellular Signal Transduction Mitotic DNA Integrity Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Component Assembly Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Metabolic Process
Tagcloud ?		aldoa atp5a1 atp5b atp5h cox5a cox5b dlst eno1 etc fbp1 glycolysis idh2 nduf2 ndufa5 ndufb10 ndufs1 ogdh organelles oxphos pgk1 rab sdha spatio suclag2 taldo1 tca uqcrh uqrb uqrc2	abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera
Tagcloud (Difference) ?		aldoa atp5a1 atp5b atp5h cox5a cox5b dlst eno1 etc fbp1 glycolysis idh2 nduf2 ndufa5 ndufb10 ndufs1 ogdh organelles oxphos pgk1 rab sdha spatio suclag2 taldo1 tca uqcrh uqrb uqrc2	abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera
Tagcloud (Intersection) ?