IDH3A and IDH3B

Number of citations of the paper that reports this interaction (PubMedID 10601238)
0

Data Source:
HPRD (in vitro, in vivo)

		IDH3A	IDH3B
Description		isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Isocitrate Dehydrogenase Complex (NAD+)	Nucleus Mitochondrion Mitochondrial Matrix Isocitrate Dehydrogenase Complex (NAD+)
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Metal Ion Binding NAD Binding	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Protein Binding Electron Transfer Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NAD Binding
	Biological Process	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Isocitrate Metabolic Process	Tricarboxylic Acid Cycle Isocitrate Metabolic Process
Pathways		Citric acid cycle (TCA cycle) Mitochondrial protein degradation	Citric acid cycle (TCA cycle)
Drugs		NADH Manganese Xanthinol Copper	NADH
Diseases			Retinitis pigmentosa (RP)
GWAS		Eyebrow thickness ( 26926045)
Interacting Genes		7 interacting genes: IDH3B IDH3G MBNL1 PRPF6 RAB4A SF1 SUMO4	6 interacting genes: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35
Entrez ID		3419	3420
HPRD ID		03094	05163
Ensembl ID		ENSG00000166411	ENSG00000101365
Uniprot IDs		B4DJB4 B7Z9J8 P50213	A0A087WZN1 A0A087X2E5 O43837
PDB IDs		5GRE 5GRF 5GRH 5GRI 5GRL 5YVT 6KDE 6KDF 6KDY 6KE3 6L57 6L59 7CE3 8GRB 8GRD 8GRG 8GRH 8GRU 8GS5	6KDE 6KDF 6KDY 6KE3 7CE3 8GRB 8GRD 8GRU 8GS5
Enriched GO Terms of Interacting Partners?		Isocitrate Dehydrogenase (NAD+) Activity Isocitrate Dehydrogenase Complex (NAD+) Isocitrate Metabolic Process Tricarboxylic Acid Metabolic Process Tricarboxylic Acid Cycle NAD Binding Spliceosomal Complex Assembly Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor RNA Splicing MRNA Processing Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome SUMO Ligase Complex MRNA Metabolic Process Insulin-responsive Compartment U2AF Complex MRNA 3'-splice Site Recognition Spliceosomal Complex Magnesium Ion Binding MRNA Splicing, Via Spliceosome Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions	Isocitrate Dehydrogenase (NAD+) Activity Isocitrate Dehydrogenase Complex (NAD+) Isocitrate Metabolic Process Tricarboxylic Acid Metabolic Process Tricarboxylic Acid Cycle NAD Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor GATOR1 Complex Binding Septin Cytoskeleton Protein-arginine Omega-N Monomethyltransferase Activity N-methyltransferase Activity Histone H4R3 Methyltransferase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Cellular Response To Methionine Magnesium Ion Binding
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