NHSL2 and YWHAH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NHSL2	YWHAH
Description		NHS like 2	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Mitochondrion Cytosol Plasma Membrane Intercalated Disc Synapse Extracellular Exosome Presynapse Glutamatergic Synapse Cerebellar Granule Cell To Purkinje Cell Synapse
	Molecular Function	Protein Binding	Actin Binding Insulin-like Growth Factor Receptor Binding Protein Binding Sodium Channel Regulator Activity Enzyme Binding Protein Domain Specific Binding Nuclear Glucocorticoid Receptor Binding Identical Protein Binding Transmembrane Transporter Binding Protein Heterodimerization Activity
	Biological Process	Cell Differentiation	Regulation Of Sodium Ion Transport Glucocorticoid Catabolic Process Intracellular Protein Transport Signal Transduction Intracellular Protein Localization Substantia Nigra Development Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Regulation Of Neuron Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of Synaptic Plasticity Negative Regulation Of Dendrite Morphogenesis Membrane Depolarization During Action Potential Presynaptic Modulation Of Chemical Synaptic Transmission
Pathways			Activation of BAD and translocation to mitochondria Translocation of SLC2A4 (GLUT4) to the plasma membrane RHO GTPases activate PKNs TP53 Regulates Metabolic Genes Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex SARS-CoV-1 targets host intracellular signalling and regulatory pathways SARS-CoV-2 targets host intracellular signalling and regulatory pathways Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Platelet count ( 32888494) Plateletcrit ( 32888494)	Post bronchodilator FEV1 ( 26634245) Type 2 diabetes ( 30297969)
Interacting Genes		25 interacting genes: ABI3 ARID4B ATXN1 BTRC CLIC1 CTTN DYNLT1 GORASP2 HSF2BP INCA1 MAPK9 MTUS2 MYO15B NCK1 NCK2 PIH1D2 PLK1 PPP1R13B SH3RF1 SORBS3 TFCP2 TP53BP2 TRAF2 YWHAG YWHAH	69 interacting genes: ABL1 ARHGEF28 BAD BCR BRAF CCDC125 CDC25B CDC25C CDC42 CDK16 CDKN1B CHRNA4 CREBBP EPB41L2 EPB41L3 ESR1 ESR2 EXO1 GREM1 HSPB1 ILF3 ING1 KANK1 KCNH2 KCNK15 KCNK3 KCNK9 KLC3 KRT18 MAP3K3 MAP3K5 MARK4 MDM4 MED1 MST1R NCAM2 NCOA1 NCOA2 NCOA3 NEDD4L NEK1 NHSL2 NR3C1 NRIP1 PARD3 PARD6A PARD6B PCNT PDPK1 PRKCI PRKN PTH1R RAF1 REM1 RIMS1 RIMS2 RPH3A SAMSN1 SNCA SRC THRA TLX2 TNFAIP3 TPH1 TSC1 TSC2 YWHAE YWHAG ZFP36
Entrez ID		340527	7533
HPRD ID		15001	00215
Ensembl ID		ENSG00000204131	ENSG00000128245
Uniprot IDs		A0A0J9YY72 Q5HYW2	Q04917 Q9H4N8
PDB IDs			2C63 2C74 7NMZ
Enriched GO Terms of Interacting Partners?		Cytoplasm Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Signaling Pathway Signaling Adaptor Activity Positive Regulation Of Protein Metabolic Process Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Vesicle Membrane Signal Transduction Lamellipodium Organization Positive Regulation Of Translation In Response To Stress Positive Regulation Of Actin Filament Polymerization Signal Complex Assembly Regulation Of Biological Quality Positive Regulation Of Supramolecular Fiber Organization Substrate-dependent Cell Migration, Cell Extension Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Translational Initiation In Response To Stress Receptor Tyrosine Kinase Binding Intracellular Signal Transduction TORC1 Signaling Positive Regulation Of Programmed Cell Death Modification Of Postsynaptic Actin Cytoskeleton Negative Regulation Of PERK-mediated Unfolded Protein Response Positive Regulation Of Cytoskeleton Organization Cytosol Regulation Of Protein Metabolic Process Positive Regulation Of Protein-containing Complex Assembly Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of PERK-mediated Unfolded Protein Response TOR Signaling Insulin-like Growth Factor Receptor Binding Positive Regulation Of Protein Polymerization Positive Regulation Of Signal Transduction Regulation Of Protein-containing Complex Assembly Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription By RNA Polymerase II Modification Of Postsynaptic Structure Modification Of Synaptic Structure Cytoskeletal Anchor Activity	Intracellular Signal Transduction Nuclear Receptor-mediated Signaling Pathway Cytosol Regulation Of Cell Communication Regulation Of Signaling Regulation Of Programmed Cell Death Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Developmental Process Regulation Of Biological Quality PAR Polarity Complex Regulation Of Intracellular Signal Transduction Regulation Of Transport Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Protein Phosphorylation Regulation Of Membrane Potential Regulation Of Apoptotic Process Regulation Of Vesicle-mediated Transport Cell Junction Organization Negative Regulation Of Apoptotic Process Phosphorylation Positive Regulation Of Metabolic Process Enzyme Binding Negative Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Regulation Of Multicellular Organismal Process Response To Lipid Cellular Response To Hormone Stimulus Hormone-mediated Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Developmental Process Positive Regulation Of Protein Localization Protein Kinase Binding Regulation Of Anatomical Structure Morphogenesis Developmental Process Cytoskeleton Organization Cellular Response To Lipid Positive Regulation Of Intracellular Signal Transduction Regulation Of Secretion By Cell Regulation Of Phosphorus Metabolic Process Regulation Of Protein Localization Positive Regulation Of Biosynthetic Process Protein Serine/threonine Kinase Activity Synaptic Vesicle Priming Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Protein Kinase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?