HES1 and SIRT1

  • Number of citations of the paper that reports this interaction (PMID 12535671)
  • 42
  • Data Source:
  • HPRD (in vivo)

HES1

SIRT1

Gene Name hes family bHLH transcription factor 1 sirtuin 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 33 interactors: APCS APH1A ASGR2 CSNK1E FANCA FANCE FANCF FANCG FANCL FHL1 FOXG1 GAPDH HDAC6 HES6 HEY2 HMGB1 HMGCL ID1 ID2 ID3 ID4 JAK2 LTBR NR4A1 NUDT3 PRKCA PTK2 SIRT1 STAT3 TLE1 TLE2 UBQLN1 YWHAB 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR
Entrez ID 3280 23411
HPRD ID 00770 08381
Ensembl ID ENSG00000114315 ENSG00000096717
Uniprot IDs Q14469 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 4I5I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alterations  anatomic  astrocytoma  astrocytomas  biology  braf  grade  hey1  hey2  implicated  inhibiting  interference  much  needed  neoplastic  notch  notch1  notch2  overexpressed  pa  pas  pediatric  pilocytic  res186  res259  secretase  tumorigenesis  variable  viable 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Difference) ?
alterations  anatomic  astrocytoma  astrocytomas  biology  braf  grade  hey1  hey2  implicated  inhibiting  interference  much  needed  neoplastic  notch  notch1  notch2  overexpressed  pa  pas  pediatric  pilocytic  res186  res259  secretase  tumorigenesis  variable  viable 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Intersection) ?