SIRT1 and HNF4A

  • Number of citations of the paper that reports this interaction (PMID 15744310)
  • 578
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

SIRT1

HNF4A

Gene Name sirtuin 1 hepatocyte nuclear factor 4, alpha
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR 62 interactors: ANP32B COPS5 CREBBP ESR1 FOXO1 GTF2B GTF2H1 HDAC3 HDAC4 HNF1A MAPK1 MAPK14 MAPK3 MECR MED1 MED10 MED14 MED16 MED17 MED21 MED24 MED7 NCOA1 NCOA2 NCOA6 NCOR2 NPPA NR0B2 NR1I3 NR2C2 NR2F1 NRBF2 NRIP1 PCBD1 PIAS4 PNRC1 PNRC2 PPARGC1A PPARGC1B PRKAA2 PRMT1 PROX1 RNF4 SIRT1 SMAD2 SMAD3 SMAD4 SP1 SREBF1 SREBF2 SUB1 SUMO1 SUMO2 TAF6 TAF9 TBP TGS1 TP53 TRIM24 UBE2I XPO1 ZNHIT3
Entrez ID 23411 3172
HPRD ID 08381 02612
Ensembl ID ENSG00000096717 ENSG00000101076
Uniprot IDs A8K128 B0QZ35 E9PC49 Q96EB6 F1D8S2 F1D8T0 F1D8T1 P41235
PDB IDs 4I5I 1PZL 3CBB 3FS1 4B7W 4IQR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
bmi1  catalyze  cdx2  differentiating  ectoderm  eed  endoderm  h2ak119ub1  h3k9me3  hes  house  kind1  lineage  lineages  map2  mef2c  mesoderm  modifiers  necessitates  pcg  polycomb  prcs  qrt  ring1b  sox1  specification  suz12  tbx5  transcripts 
Tagcloud (Difference) ?
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
bmi1  catalyze  cdx2  differentiating  ectoderm  eed  endoderm  h2ak119ub1  h3k9me3  hes  house  kind1  lineage  lineages  map2  mef2c  mesoderm  modifiers  necessitates  pcg  polycomb  prcs  qrt  ring1b  sox1  specification  suz12  tbx5  transcripts 
Tagcloud (Intersection) ?