SIRT1 and STK4

  • Number of citations of the paper that reports this interaction (PMID 21212262)
  • 7
  • Data Source:
  • BioGRID (enzymatic study)

SIRT1

STK4

Gene Name sirtuin 1 serine/threonine kinase 4
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR 16 interactors: AKT1 CASP3 CNKSR1 CSN1S1 HIST2H2BE IL2RG LATS1 MBP NEDD4 PRKRIR RASSF1 RASSF5 SAV1 SGMS1 SIRT1 TP53
Entrez ID 23411 6789
HPRD ID 08381 05395
Ensembl ID ENSG00000096717 ENSG00000101109
Uniprot IDs A8K128 B0QZ35 E9PC49 Q96EB6 Q13043
PDB IDs 4I5I 2JO8 3COM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
abl1  centered  coactivator  damage  elicits  hematologic  hematological  hippo  inactivation  instability  lethal  malignancies  myeloma  notably  oncogene  ongoing  pervasive  presenting  proapoptotic  relevance  relocalization  restores  selectively  serine  synthetic  threonine  triggering  triggers  yap1 
Tagcloud (Difference) ?
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
abl1  centered  damage  elicits  hematologic  hematological  hippo  inactivation  instability  lethal  malignancies  myeloma  notably  oncogene  ongoing  pervasive  presenting  proapoptotic  relevance  relocalization  restores  selectively  serine  synthetic  threonine  triggering  triggers  yap1 
Tagcloud (Intersection) ?
coactivator