HES1 and ALK

  • Number of citations of the paper that reports this interaction (PubMedID 35640677)
  • 50
  • Data Source:
  • BioGRID (enzymatic study)

HES1

ALK

Description hes family bHLH transcription factor 1 ALK receptor tyrosine kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcoholic chronic pancreatitis ( 28754779)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)
  • Thyroid stimulating hormone levels ( 30367059 32769997)
  • Adiponectin levels (BMI-adjusted) ( 26299439)
  • Body mass index ( 25673413)
  • Body size at age 10 ( 32376654)
  • Carbamazepine-induced reaction with eosinophilia and systemic symptoms ( 31066027)
  • Carbamazepine-induced serious cutaneous adverse reaction ( 31066027)
  • Dentures ( 31235808)
  • Gestational age at birth (child effect) ( 31194736)
  • Glucose homeostasis traits ( 25524916)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Simvastatin-induced myopathy ( 31220337)
  • Spontaneous coronary artery dissection ( 32887874)
  • Systolic blood pressure ( 26969751)
  • Total cholesterol levels ( 33339817)
Interacting Genes 36 interacting genes: ALK APCS APH1A ASGR2 CSNK1E FANCA FANCE FANCF FANCG FANCL FHL1 FOXG1 GAPDH HDAC6 HES6 HEY2 HMGB1 HMGCL ID1 ID2 ID3 ID4 JAK2 LTBR NHLH2 NR4A1 NUDT3 PRKCA PTK2 RUNX2 SIRT1 STAT3 TLE1 TLE2 UBQLN1 YWHAB 19 interacting genes: APBB1 DUSP19 ERBB2 HES1 IKBKG IRS1 JAK3 MDK NPM1 PIK3R1 PLCG1 PPM1A PTN PTPN11 PTPRZ1 SHC1 SHC3 TNFRSF8 ZC3HC1
Entrez ID 3280 238
HPRD ID 00770 00104
Ensembl ID ENSG00000114315 ENSG00000171094
Uniprot IDs Q14469 A0A0K2YUJ3 B6D4Y2 Q9UM73
PDB IDs 2MH3 7C4O 2KUP 2KUQ 2XB7 2XBA 2XP2 2YFX 2YHV 2YJR 2YJS 2YS5 2YT2 3AOX 3L9P 3LCS 3LCT 4ANL 4ANQ 4ANS 4CCB 4CCU 4CD0 4CLI 4CLJ 4CMO 4CMT 4CMU 4CNH 4CTB 4CTC 4DCE 4FNW 4FNX 4FNY 4FNZ 4FOB 4FOC 4FOD 4JOA 4MKC 4TT7 4Z55 5A9U 5AA8 5AA9 5AAA 5AAB 5AAC 5FTO 5FTQ 5IMX 5IUG 5IUH 5IUI 5KZ0 5VZ5 6AT9 6CDT 6E0R 6EBW 6EDL 6MX8 7BTT 7JY4 7JYR 7JYS 7JYT 7LRZ 7LS0 7MZW 7MZY 7N00 7NWZ 7NX3 7NX4 7R7K 7R7R 8ARJ 9G5I 9GBE
Enriched GO Terms of Interacting Partners?
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