PDZRN4 and LNX2

Number of citations of the paper that reports this interaction (PMID 22889411)
1

Data Source:
BioGRID (two hybrid)

		PDZRN4	LNX2
Gene Name		PDZ domain containing ring finger 4	ligand of numb-protein X 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Protein Ubiquitination	Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Multiple sclerosis ( 19010793) Protein quantitative trait loci ( 18464913)	Large B-cell lymphoma ( 21471979)
Protein-Protein Interactions		2 interactors: LNX1 LNX2	17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2
Entrez ID		29951	222484
HPRD ID		15116	10042
Ensembl ID		ENSG00000165966	ENSG00000139517
Uniprot IDs		B4DGD1 Q6ZMN7	Q8N448
PDB IDs			2VWR
Enriched GO Terms of Interacting Partners?		Protein Homooligomerization Protein Oligomerization Protein Complex Assembly Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Component Assembly	Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication
Tagcloud ?		5k3 alpl armitage beadchip bovinesnp50 bull capn1 catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36	amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Difference) ?		5k3 alpl armitage beadchip bovinesnp50 bull capn1 catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36	amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Intersection) ?