DDIT4L and GEMIN6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DDIT4L	GEMIN6
Description		DNA damage inducible transcript 4 like	gem nuclear organelle associated protein 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Signal Transduction	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Nose size ( 27182965)
Interacting Genes		155 interacting genes: ABCB11 ACY3 AFMID AIDA AKT1 ARK2N ARPIN BAG4 BANF2 BCL2L14 BID C14orf119 C19orf25 C5orf22 CABP5 CALCOCO2 CALM1 CALM2 CALM3 CATIP CCNK CDA CDKN2D CDPF1 CHMP1A CLIC3 CLK2 CLK3 CPNE7 CRLF3 CRYBB1 DBI DNPH1 DUSP23 DUSP29 EIF4A3 EIF4EBP1 EIF4H EPHB6 EXOSC1 EXOSC5 EXOSC8 FAAP20 FADD FAM200C FHIT FHL2 FKBP6 FLNA GADD45G GEMIN6 GPKOW GRB2 GUCA1A HDAC7 HMG20A HSPB7 IL36RN IMPDH1 KANK2 KCTD9 KDM8 KRT34 KRTAP5-6 LENG1 LGALS14 LGALSL LMO1 LRATD2 LSM3 LSM5 LSM7 MAP3K7CL MAPRE2 MAPRE3 MEMO1 MIEN1 MKRN3 MLX MORF4L2 MT1M MYG1 MYLIP NAA10 NAV1 NEK6 NGB NHLRC4 NME7 NQO2 NR2C2AP NUDT2 NUDT22 NXT2 PARVG PCBP3 PDE4C PFKFB1 PLSCR4 PM20D2 PMVK PPCDC PPIL1 PPP1R27 PRKAB2 PRPF40A PSMA1 PSMB9 PTS PUF60 RAB32 RFC5 RFPL3 RPIA RPL22 RPRD1B SCOC SEC22A SEPTIN1 SEPTIN3 SEPTIN5 SH3BGRL3 SNRPA SNRPG SREK1IP1 STK16 STK4 SULT2B1 TBC1D22B TCL1A TCP11L1 TEKT4 TEX14 TFPT TNS2 TOLLIP TRIM73 TSEN15 TSSK3 TTC5 TXN TXNL4A TYW3 UBASH3A UBTFL1 VBP1 VCX2 VPS26C YES1 YOD1 YPEL5 ZNF593 ZNF76 ZNF765 ZSCAN23	16 interacting genes: ACOT11 DDIT4L GEMIN7 NUFIP1 RASL11B RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STRAP TOX4
Entrez ID		115265	79833
HPRD ID		09663	06110
Ensembl ID		ENSG00000145358	ENSG00000152147
Uniprot IDs		Q96D03	Q8WXD5
PDB IDs			1Y96 7BBL
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoplasm Nucleus MRNA Splicing, Via Spliceosome MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Identical Protein Binding Cytosol U4/U6 X U5 Tri-snRNP Complex MRNA Processing RNA Splicing Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Lsm1-7-Pat1 Complex RNA Processing Nucleobase-containing Compound Metabolic Process Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Lsm2-8 Complex Protein Serine/threonine Kinase Activator Activity Spliceosomal Complex U6 SnRNP Protein Kinase Binding Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Nucleolar Exosome (RNase Complex) U2-type Precatalytic Spliceosome Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Nucleoplasm Titin Binding Septin Ring Septin Complex Cell Division Site Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Detection Of Calcium Ion Nucleobase-containing Compound Catabolic Process Regulation Of Cell Communication By Electrical Coupling Nuclear Exosome (RNase Complex) U2-type Prespliceosome Exosome (RNase Complex) Phosphate-containing Compound Metabolic Process Protein Phosphatase Activator Activity Microtubule Cytoskeleton Calyx Of Held U1 SnRNP RNA Metabolic Process Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Regulator Activity	SMN-Sm Protein Complex 7-methylguanosine Cap Hypermethylation Spliceosomal SnRNP Assembly U2 SnRNP U4 SnRNP Methylosome Protein-RNA Complex Assembly Small Nuclear Ribonucleoprotein Complex U1 SnRNP U7 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions PICln-Sm Protein Complex RNA Methylation Catalytic Step 2 Spliceosome RNA Splicing Macromolecule Methylation Protein-containing Complex Assembly MRNA Processing Precatalytic Spliceosome Protein-containing Complex Organization RNA Modification Spliceosomal Complex RNA Processing Methylation MRNA Metabolic Process Ribonucleoprotein Complex U2 SnRNP Binding Cellular Component Assembly Telomerase Holoenzyme Complex RNA Metabolic Process RNA Binding Histone Pre-mRNA DCP Binding Spliceosomal Tri-snRNP Complex Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process SMN Complex U2-type Prespliceosome Telomerase RNA Binding Protein Methylation Pre-mRNA Branch Point Binding MRNA Branch Site Recognition
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