DDIT4L and TEX14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DDIT4L	TEX14
Description		DNA damage inducible transcript 4 like	testis expressed 14, intercellular bridge forming factor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Midbody Intercellular Bridge Extracellular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Binding ATP Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Signal Transduction	Mitotic Spindle Assembly Checkpoint Signaling Male Meiotic Nuclear Division Attachment Of Spindle Microtubules To Kinetochore Negative Regulation Of Cytokinesis Intercellular Bridge Organization Cell Division Mitotic Sister Chromatid Separation Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Nose size ( 27182965)	Age at first birth ( 34211149) Chronotype ( 30696823) Cognitive function ( 25644384) Estimated glomerular filtration rate ( 31152163) Iron status biomarkers (ferritin levels) ( 25352340) Neutrophil count ( 32888494) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278) Testicular germ cell tumor ( 23666239 23666240 25877299 28604728 28604732) Type 2 diabetes ( 30054458) White blood cell count ( 32888494)
Interacting Genes		155 interacting genes: ABCB11 ACY3 AFMID AIDA AKT1 ARK2N ARPIN BAG4 BANF2 BCL2L14 BID C14orf119 C19orf25 C5orf22 CABP5 CALCOCO2 CALM1 CALM2 CALM3 CATIP CCNK CDA CDKN2D CDPF1 CHMP1A CLIC3 CLK2 CLK3 CPNE7 CRLF3 CRYBB1 DBI DNPH1 DUSP23 DUSP29 EIF4A3 EIF4EBP1 EIF4H EPHB6 EXOSC1 EXOSC5 EXOSC8 FAAP20 FADD FAM200C FHIT FHL2 FKBP6 FLNA GADD45G GEMIN6 GPKOW GRB2 GUCA1A HDAC7 HMG20A HSPB7 IL36RN IMPDH1 KANK2 KCTD9 KDM8 KRT34 KRTAP5-6 LENG1 LGALS14 LGALSL LMO1 LRATD2 LSM3 LSM5 LSM7 MAP3K7CL MAPRE2 MAPRE3 MEMO1 MIEN1 MKRN3 MLX MORF4L2 MT1M MYG1 MYLIP NAA10 NAV1 NEK6 NGB NHLRC4 NME7 NQO2 NR2C2AP NUDT2 NUDT22 NXT2 PARVG PCBP3 PDE4C PFKFB1 PLSCR4 PM20D2 PMVK PPCDC PPIL1 PPP1R27 PRKAB2 PRPF40A PSMA1 PSMB9 PTS PUF60 RAB32 RFC5 RFPL3 RPIA RPL22 RPRD1B SCOC SEC22A SEPTIN1 SEPTIN3 SEPTIN5 SH3BGRL3 SNRPA SNRPG SREK1IP1 STK16 STK4 SULT2B1 TBC1D22B TCL1A TCP11L1 TEKT4 TEX14 TFPT TNS2 TOLLIP TRIM73 TSEN15 TSSK3 TTC5 TXN TXNL4A TYW3 UBASH3A UBTFL1 VBP1 VCX2 VPS26C YES1 YOD1 YPEL5 ZNF593 ZNF76 ZNF765 ZSCAN23	4 interacting genes: DDIT4L LHX3 LMO4 MEOX2
Entrez ID		115265	56155
HPRD ID		09663	12046
Ensembl ID		ENSG00000145358	ENSG00000121101
Uniprot IDs		Q96D03	Q8IWB6
PDB IDs			3WUT 3WUU
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoplasm Nucleus MRNA Splicing, Via Spliceosome MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Identical Protein Binding Cytosol U4/U6 X U5 Tri-snRNP Complex MRNA Processing RNA Splicing Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Lsm1-7-Pat1 Complex RNA Processing Nucleobase-containing Compound Metabolic Process Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Lsm2-8 Complex Protein Serine/threonine Kinase Activator Activity Spliceosomal Complex U6 SnRNP Protein Kinase Binding Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Nucleolar Exosome (RNase Complex) U2-type Precatalytic Spliceosome Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Nucleoplasm Titin Binding Septin Ring Septin Complex Cell Division Site Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Detection Of Calcium Ion Nucleobase-containing Compound Catabolic Process Regulation Of Cell Communication By Electrical Coupling Nuclear Exosome (RNase Complex) U2-type Prespliceosome Exosome (RNase Complex) Phosphate-containing Compound Metabolic Process Protein Phosphatase Activator Activity Microtubule Cytoskeleton Calyx Of Held U1 SnRNP RNA Metabolic Process Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Regulator Activity	Spinal Cord Motor Neuron Cell Fate Specification Spinal Cord Association Neuron Differentiation Motor Neuron Axon Guidance Neuron Fate Specification Cell Differentiation In Spinal Cord Cell Fate Specification Medial Motor Column Neuron Differentiation Central Nervous System Neuron Differentiation Prolactin Secreting Cell Differentiation Ventral Spinal Cord Interneuron Specification Neuron Projection Guidance Somatotropin Secreting Cell Differentiation Axon Guidance Ventral Spinal Cord Interneuron Differentiation Somite Specification Transcription Regulator Complex Positive Regulation Of Transcription By RNA Polymerase II Thyroid-stimulating Hormone-secreting Cell Differentiation Gland Development Neuron Differentiation DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Pattern Specification Process Segment Specification Positive Regulation Of DNA-templated Transcription Somite Development Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Sequence-specific DNA Binding Neuron Projection Development Neuroendocrine Cell Differentiation Spinal Cord Motor Neuron Differentiation Regulation Of Cell Fate Specification Positive Regulation Of Nucleobase-containing Compound Metabolic Process Glandular Epithelial Cell Differentiation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Pituitary Gland Development Ventricular Septum Development Neuroepithelial Cell Differentiation Forebrain Neuron Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Anatomical Structure Formation Involved In Morphogenesis Tissue Development Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Transcription By RNA Polymerase II Transcription Coregulator Binding Transcription Coactivator Binding Placenta Development Cardiac Septum Development
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