DDIT4L and DBI

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DDIT4L	DBI
Description		DNA damage inducible transcript 4 like	diazepam binding inhibitor, acyl-CoA binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Protein-lipid Complex Extracellular Exosome Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding	Fatty-acyl-CoA Binding Protein Binding Lipid Binding Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Signal Transduction	Fatty Acid Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Negative Regulation Of Protein Lipidation Positive Regulation Of Phospholipid Transport
Pathways			Mitochondrial Fatty Acid Beta-Oxidation
Drugs			Coenzyme A Hexadecanal
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Nose size ( 27182965)	Obesity-related traits ( 23251661)
Interacting Genes		155 interacting genes: ABCB11 ACY3 AFMID AIDA AKT1 ARK2N ARPIN BAG4 BANF2 BCL2L14 BID C14orf119 C19orf25 C5orf22 CABP5 CALCOCO2 CALM1 CALM2 CALM3 CATIP CCNK CDA CDKN2D CDPF1 CHMP1A CLIC3 CLK2 CLK3 CPNE7 CRLF3 CRYBB1 DBI DNPH1 DUSP23 DUSP29 EIF4A3 EIF4EBP1 EIF4H EPHB6 EXOSC1 EXOSC5 EXOSC8 FAAP20 FADD FAM200C FHIT FHL2 FKBP6 FLNA GADD45G GEMIN6 GPKOW GRB2 GUCA1A HDAC7 HMG20A HSPB7 IL36RN IMPDH1 KANK2 KCTD9 KDM8 KRT34 KRTAP5-6 LENG1 LGALS14 LGALSL LMO1 LRATD2 LSM3 LSM5 LSM7 MAP3K7CL MAPRE2 MAPRE3 MEMO1 MIEN1 MKRN3 MLX MORF4L2 MT1M MYG1 MYLIP NAA10 NAV1 NEK6 NGB NHLRC4 NME7 NQO2 NR2C2AP NUDT2 NUDT22 NXT2 PARVG PCBP3 PDE4C PFKFB1 PLSCR4 PM20D2 PMVK PPCDC PPIL1 PPP1R27 PRKAB2 PRPF40A PSMA1 PSMB9 PTS PUF60 RAB32 RFC5 RFPL3 RPIA RPL22 RPRD1B SCOC SEC22A SEPTIN1 SEPTIN3 SEPTIN5 SH3BGRL3 SNRPA SNRPG SREK1IP1 STK16 STK4 SULT2B1 TBC1D22B TCL1A TCP11L1 TEKT4 TEX14 TFPT TNS2 TOLLIP TRIM73 TSEN15 TSSK3 TTC5 TXN TXNL4A TYW3 UBASH3A UBTFL1 VBP1 VCX2 VPS26C YES1 YOD1 YPEL5 ZNF593 ZNF76 ZNF765 ZSCAN23	14 interacting genes: CYSLTR2 DDIT4L DUSP23 GSK3B LAMTOR5 MAP1LC3B NIPSNAP1 NSFL1C PFDN2 PPCDC RAD23A RAD23B TSPO UBXN2A
Entrez ID		115265	1622
HPRD ID		09663	08832
Ensembl ID		ENSG00000145358	ENSG00000155368
Uniprot IDs		Q96D03	A0A024RAF2 B8ZWD1 B8ZWD8 P07108
PDB IDs			2CB8 2FJ9
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoplasm Nucleus MRNA Splicing, Via Spliceosome MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Identical Protein Binding Cytosol U4/U6 X U5 Tri-snRNP Complex MRNA Processing RNA Splicing Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Lsm1-7-Pat1 Complex RNA Processing Nucleobase-containing Compound Metabolic Process Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Lsm2-8 Complex Protein Serine/threonine Kinase Activator Activity Spliceosomal Complex U6 SnRNP Protein Kinase Binding Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Nucleolar Exosome (RNase Complex) U2-type Precatalytic Spliceosome Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Nucleoplasm Titin Binding Septin Ring Septin Complex Cell Division Site Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Detection Of Calcium Ion Nucleobase-containing Compound Catabolic Process Regulation Of Cell Communication By Electrical Coupling Nuclear Exosome (RNase Complex) U2-type Prespliceosome Exosome (RNase Complex) Phosphate-containing Compound Metabolic Process Protein Phosphatase Activator Activity Microtubule Cytoskeleton Calyx Of Held U1 SnRNP RNA Metabolic Process Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Regulator Activity	Ubiquitin Binding Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Protein Localization To Centrosome Proteasomal Protein Catabolic Process Autophagosome Assembly Autophagosome Organization Protein Catabolic Process Proteasome Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Organelle Assembly Nuclear Membrane Reassembly Regulation Of Proteolysis Cytosol Regulation Of Ubiquitin-dependent Protein Catabolic Process Catabolic Process Vacuole Organization Polyubiquitin Modification-dependent Protein Binding Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Corticosterone Secretion Regulation Of Protein Metabolic Process Regulation Of Microtubule Anchoring At Centrosome Nuclear Membrane Organization Cysteinyl Leukotriene Receptor Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex Nucleotide-excision Repair Regulation Of Post-translational Protein Modification Macromolecule Catabolic Process Mitophagy Membrane Assembly Negative Regulation Of Protein Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Proteasome Complex Damaged DNA Binding Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Autophagy Of Mitochondrion VCP-NSFL1C Complex Negative Regulation Of Protein Localization To Centrosome Proteolysis Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
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