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DDIT4L and MIEN1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
DDIT4L
MIEN1
Description
DNA damage inducible transcript 4 like
migration and invasion enhancer 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Cytoplasmic Side Of Plasma Membrane
Membrane
Molecular Function
Protein Binding
Protein Binding
Biological Process
Negative Regulation Of Signal Transduction
Apoptotic Process
Positive Regulation Of Cell Migration
Negative Regulation Of Apoptotic Process
Positive Regulation Of Filopodium Assembly
Pathways
Drugs
Diseases
GWAS
Alcohol consumption (drinks per week) (
30643258
)
Nose size (
27182965
)
Asthma (
29273806
31619474
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Systemic lupus erythematosus (
28714469
)
Interacting Genes
155 interacting genes:
ABCB11
ACY3
AFMID
AIDA
AKT1
ARK2N
ARPIN
BAG4
BANF2
BCL2L14
BID
C14orf119
C19orf25
C5orf22
CABP5
CALCOCO2
CALM1
CALM2
CALM3
CATIP
CCNK
CDA
CDKN2D
CDPF1
CHMP1A
CLIC3
CLK2
CLK3
CPNE7
CRLF3
CRYBB1
DBI
DNPH1
DUSP23
DUSP29
EIF4A3
EIF4EBP1
EIF4H
EPHB6
EXOSC1
EXOSC5
EXOSC8
FAAP20
FADD
FAM200C
FHIT
FHL2
FKBP6
FLNA
GADD45G
GEMIN6
GPKOW
GRB2
GUCA1A
HDAC7
HMG20A
HSPB7
IL36RN
IMPDH1
KANK2
KCTD9
KDM8
KRT34
KRTAP5-6
LENG1
LGALS14
LGALSL
LMO1
LRATD2
LSM3
LSM5
LSM7
MAP3K7CL
MAPRE2
MAPRE3
MEMO1
MIEN1
MKRN3
MLX
MORF4L2
MT1M
MYG1
MYLIP
NAA10
NAV1
NEK6
NGB
NHLRC4
NME7
NQO2
NR2C2AP
NUDT2
NUDT22
NXT2
PARVG
PCBP3
PDE4C
PFKFB1
PLSCR4
PM20D2
PMVK
PPCDC
PPIL1
PPP1R27
PRKAB2
PRPF40A
PSMA1
PSMB9
PTS
PUF60
RAB32
RFC5
RFPL3
RPIA
RPL22
RPRD1B
SCOC
SEC22A
SEPTIN1
SEPTIN3
SEPTIN5
SH3BGRL3
SNRPA
SNRPG
SREK1IP1
STK16
STK4
SULT2B1
TBC1D22B
TCL1A
TCP11L1
TEKT4
TEX14
TFPT
TNS2
TOLLIP
TRIM73
TSEN15
TSSK3
TTC5
TXN
TXNL4A
TYW3
UBASH3A
UBTFL1
VBP1
VCX2
VPS26C
YES1
YOD1
YPEL5
ZNF593
ZNF76
ZNF765
ZSCAN23
15 interacting genes:
ARID5A
DDIT4L
GORASP2
HDAC7
HIVEP1
HLX
HMGB1
HMGB2
NLGN3
POU6F2
REL
RNF126
TRIP6
VENTX
ZBTB32
Entrez ID
115265
84299
HPRD ID
09663
12681
Ensembl ID
ENSG00000145358
ENSG00000141741
Uniprot IDs
Q96D03
J3KTI2
Q9BRT3
PDB IDs
2LJK
Enriched GO Terms of Interacting Partners
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Protein Binding
Cytoplasm
Nucleus
MRNA Splicing, Via Spliceosome
MRNA Metabolic Process
RNA Splicing, Via Transesterification Reactions
Identical Protein Binding
Cytosol
U4/U6 X U5 Tri-snRNP Complex
MRNA Processing
RNA Splicing
Negative Regulation Of Calcium Ion Export Across Plasma Membrane
Adenylate Cyclase Activator Activity
Lsm1-7-Pat1 Complex
RNA Processing
Nucleobase-containing Compound Metabolic Process
Transporter Inhibitor Activity
Regulation Of Calcium Ion Export Across Plasma Membrane
Lsm2-8 Complex
Protein Serine/threonine Kinase Activator Activity
Spliceosomal Complex
U6 SnRNP
Protein Kinase Binding
Negative Regulation Of High Voltage-gated Calcium Channel Activity
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Nucleolar Exosome (RNase Complex)
U2-type Precatalytic Spliceosome
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Nucleoplasm
Titin Binding
Septin Ring
Septin Complex
Cell Division Site
Cytoplasmic Exosome (RNase Complex)
RNA Exonuclease Activity
Detection Of Calcium Ion
Nucleobase-containing Compound Catabolic Process
Regulation Of Cell Communication By Electrical Coupling
Nuclear Exosome (RNase Complex)
U2-type Prespliceosome
Exosome (RNase Complex)
Phosphate-containing Compound Metabolic Process
Protein Phosphatase Activator Activity
Microtubule Cytoskeleton
Calyx Of Held
U1 SnRNP
RNA Metabolic Process
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Calcium Channel Regulator Activity
DNA Binding
Regulation Of Transcription By RNA Polymerase II
DNA Geometric Change
Supercoiled DNA Binding
Regulation Of Interferon-beta Production
Regulation Of Nucleobase-containing Compound Metabolic Process
DNA Topological Change
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
RAGE Receptor Binding
Regulation Of Cytokine Production
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
T-helper 1 Cell Differentiation
Regulation Of Non-canonical NF-kappaB Signal Transduction
DNA Binding, Bending
DNA Conformation Change
Four-way Junction DNA Binding
V(D)J Recombination
Transcription Factor Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Chromatin
Regulation Of Type I Interferon Production
Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Nuclear Thyroid Hormone Receptor Binding
Negative Regulation Of Alpha-beta T Cell Differentiation
Regulation Of Primary Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation
Inflammatory Response To Antigenic Stimulus
Chemoattractant Activity
Condensed Chromosome
Cellular Response To Lipopolysaccharide
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Sequence-specific DNA Binding
T-helper Cell Differentiation
Positive Regulation Of Interferon-beta Production
DNA-binding Transcription Factor Binding
Cellular Response To Molecule Of Bacterial Origin
T Cell Differentiation Involved In Immune Response
Positive Regulation Of Epithelial Cell Proliferation
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Somatic Cell DNA Recombination
Positive Chemotaxis
Transcription Corepressor Activity
Negative Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
CD4-positive, Alpha-beta T Cell Differentiation
Regulation Of Adaptive Immune Response
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