WDR33 and MIR34B

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		WDR33	MIR34B
Description		WD repeat domain 33	microRNA 34b
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Collagen Trimer Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	RNA Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Postreplication Repair MRNA Processing Spermatogenesis MRNA 3'-end Processing	Negative Regulation Of Cell Population Proliferation MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Coronary artery calcification ( 23870195) Coronary artery disease ( 29212778) White blood cell count ( 32888494)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756)
Interacting Genes		19 interacting genes: CDK4 EEF1G GIT1 KAT7 MIR19A MIR19B1 MIR34B MIR92A2 PFN2 PRMT1 RBM48 SH3GL3 TGFBR1 TP53 UBC UTP14A WWOX ZBTB16 ZHX1	109 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2 ATXN2L C1QBP CDC5L CELF1 CELF2 CPSF1 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MTERF3 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PIP5K1A PLOD1 PTBP1 PTBP3 PTCD3 PUF60 PURA PURB QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBM45 RBM4B RTCA RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM56 U2SURP UPF1 USP36 UTP20 WDR33 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		55339	407041
HPRD ID		11680
Ensembl ID		ENSG00000136709	ENSG00000207811
Uniprot IDs		Q9C0J8
PDB IDs		6BLY 6BM0 6DNH 6F9N 6FUW 6URG 6URO 8E3I 8E3Q 8R8R
Enriched GO Terms of Interacting Partners?		Regulation Of Extracellular Matrix Assembly Response To Actinomycin D Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Post-transcriptional Gene Silencing Negative Regulation Of Matrix Metallopeptidase Secretion Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Differentiation Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Cellular Response To Molecule Of Bacterial Origin Negative Regulation Of Developmental Process Regulation Of Extracellular Matrix Organization Regulation Of Heart Growth Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Extracellular Matrix Assembly Cellular Response To Bacterial Lipopeptide Positive Regulation Of Protein-containing Complex Assembly Regulation Of Cell Growth Response To Bacterial Lipoprotein Negative Regulation Of Fibroblast Migration Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Multicellular Organismal Development Regulation Of Cell Cycle Regulation Of Stem Cell Proliferation RISC Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Organ Growth Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression MRNA Destabilization Regulation Of Cell Differentiation RNA Destabilization Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Epithelial To Mesenchymal Transition	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Splicing, Via Transesterification Reactions Nucleus Regulation Of MRNA Metabolic Process Nucleoplasm Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Ribonucleoprotein Complex Catalytic Step 2 Spliceosome Spliceosomal Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translation Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding MiRNA Binding Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Negative Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process RNA Stabilization TRNA Aminoacylation MRNA Stabilization Regulation Of Primary Metabolic Process Regulation Of RNA Stability RNA Transport Regulation Of MRNA Stability U2 SnRNP Positive Regulation Of Gene Expression Regulation Of Metabolic Process Ligase Activity Protein-RNA Complex Assembly
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