KIF1A and TSPOAP1

Number of citations: 69 (PubMedID 24722188)
Data Source: BioGRID (two hybrid)

		KIF1A	TSPOAP1
Name		kinesin family member 1A	TSPO associated protein 1
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Kinesin Complex Microtubule Membrane Axon Dendrite Cytoplasmic Vesicle Cell Projection Neuron Projection Synapse Perinuclear Region Of Cytoplasm Neuronal Dense Core Vesicle Neuronal Dense Core Vesicle Membrane Axon Cytoplasm	Cytoplasm Mitochondrion Cytosol Calyx Of Held Glutamatergic Synapse
	Molecular Function	Nucleotide Binding Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Hydrolase Activity Isomerase Activity ATP Hydrolysis Activity Identical Protein Binding Metal Ion Binding	Protein Binding Benzodiazepine Receptor Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
	Biological Process	Microtubule-based Movement Anterograde Axonal Transport Transport Along Microtubule Vesicle-mediated Transport Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Dense Core Granule Cytoskeletal Transport Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport	Neuromuscular Synaptic Transmission Regulation Of Neurotransmitter Secretion Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Pregnenolone biosynthesis Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs		Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Phosphoaminophosphonic Acid-Adenylate Ester	None
GWAS		Height ( 31562340 ) Hip circumference adjusted for BMI ( 34021172 ) Response to placebo treatment in childhood asthma (FVC change) ( 31557306 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: ICAM1	None recorded
Interacting Genes		32 interacting genes: ADAMTSL4 AR DSCR9 DYRK1A ESR1 FXR2 GIT1 MDFI MED1 MID2 MKRN3 MTUS2 NOTCH2NLA PCNT PKNOX1 PLSCR1 PPARG PSMA3 RBPMS RFX6 RGS20 RNF31 RSPH1 RXRA SP1 SPRY2 TNS2 TRAF1 TRIM27 TRIP6 TSPOAP1 VPS26C	19 interacting genes: ANKRD11 ARNT2 BEND5 CACNA1A CADPS2 CEP76 DISC1 DLGAP2 DLX2 GPRASP2 KHDRBS1 KIF1A MVP NDE1 RAPGEF4 REL TCF4 TSC22D4 TSPO
Entrez ID		547	9256
HPRD ID		03156	09832
Ensembl ID		ENSG00000130294	ENSG00000005379
Uniprot IDs		A0A3B3IT28 A0A3B3ITE5 A0A3B3ITF7 A0A3B3ITK3 A0A3B3ITW6 A0A3B3IU40 A0A3B3IUA1 A0A3F2YNW9 C9JBH1 Q12756	A7E2C5 B2RUT8 B7ZVZ7 O95153 X5DQQ3
PDB IDs		4EGX 4EJQ 4UXO 4UXP 4UXR 4UXS 8UTN 8UTO 8UTP 8UTQ 8UTR 8UTS 8UTT 8UTU 8UTV 8UTW 8UTY	Not available
GO Terms Enriched among Interactors		Regulation Of Cell Communication Regulation Of Signaling Identical Protein Binding LBD Domain Binding Regulation Of Signal Transduction Nuclear Receptor-mediated Signaling Pathway Transcription Coregulator Binding Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of RNA Metabolic Process Nuclear Receptor Activity Cellular Response To Estrogen Stimulus Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Monocyte Differentiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Hormone-mediated Signaling Pathway Cytoplasm Nuclear Steroid Receptor Activity Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Transcription By RNA Polymerase II Mammary Gland Branching Involved In Pregnancy DNA Binding Domain Binding Positive Regulation Of Macromolecule Biosynthetic Process Zinc Ion Binding Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Lipoprotein Transport Negative Regulation Of Signal Transduction Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Cell Communication Negative Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Signaling Enzyme Binding MRNA Transcription By RNA Polymerase II Organ Growth Positive Regulation Of Signal Transduction Transcription Coactivator Binding Transcription Cis-regulatory Region Binding DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Prostate Gland Growth	Kinesin Complex Synapse Secretory Granule Localization Establishment Of Vesicle Localization Vesicle Localization Glial Cell Migration Hematopoietic Stem Cell Homeostasis