KIF1A and TNS2

Number of citations of the paper that reports this interaction (PubMedID 24722188)
69

Data Source:
BioGRID (two hybrid)

		KIF1A	TNS2
Description		kinesin family member 1A	tensin 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Kinesin Complex Microtubule Membrane Axon Dendrite Cytoplasmic Vesicle Cell Projection Neuron Projection Synapse Perinuclear Region Of Cytoplasm Neuronal Dense Core Vesicle Neuronal Dense Core Vesicle Membrane Axon Cytoplasm	Cytoplasm Plasma Membrane Focal Adhesion Membrane Anchoring Junction
	Molecular Function	Nucleotide Binding Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Hydrolase Activity Isomerase Activity ATP Hydrolysis Activity Identical Protein Binding Metal Ion Binding	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Zinc Ion Binding Lipid Binding Hydrolase Activity Kinase Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Microtubule-based Movement Anterograde Axonal Transport Transport Along Microtubule Vesicle-mediated Transport Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Dense Core Granule Cytoskeletal Transport Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport	Kidney Development Negative Regulation Of Cell Population Proliferation Response To Muscle Activity Cellular Homeostasis Collagen Metabolic Process Multicellular Organism Growth Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway Multicellular Organismal-level Homeostasis
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs		Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Response to placebo treatment in childhood asthma (FVC change) ( 31557306)
Interacting Genes		32 interacting genes: ADAMTSL4 AR DSCR9 DYRK1A ESR1 FXR2 GIT1 MDFI MED1 MID2 MKRN3 MTUS2 NOTCH2NLA PCNT PKNOX1 PLSCR1 PPARG PSMA3 RBPMS RFX6 RGS20 RNF31 RSPH1 RXRA SP1 SPRY2 TNS2 TRAF1 TRIM27 TRIP6 TSPOAP1 VPS26C	150 interacting genes: ADCK5 AMMECR1 AP1S2 AQP1 ARID5A ASB3 AXL BAHD1 BLZF1 BRCA1 C11orf87 C1orf94 CATSPER1 CCDC33 CNNM3 COX6B2 CPSF7 CRX CSNK1E CTSZ DCAF11 DCAF8 DDIT4L DLC1 DOK3 DZIP1 DZIP3 EGFR ENKD1 EPB41L4A EPDR1 EPS8L2 ERBB2 ERBB3 ERBB4 FABP7 FAM114A1 FAM228A FASLG FGF21 FGFR1 FOXO1 GATA1 GBA3 GFI1B HOXA1 HOXB9 HOXC8 HUWE1 ID2 IHO1 INO80B ITGB3 ITGB5 ITGB7 KCTD9 KIF1A KIT KPRP KRT76 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP13-1 KRTAP13-2 KRTAP23-1 KRTAP3-1 KRTAP4-4 KRTAP6-3 LASP1 LPXN LUZP4 MET MGAT5B MPEG1 MT2A MTDH MYBPHL MYH7B MYPOP NBPF19 NMU NOTCH2NLA NT5C NUBP2 OBSL1 OTX1 PATZ1 PER1 PHF1 PIN1 PKP1 PLB1 PLK3 PLSCR3 POLR1H POLR3F PRR22 RAMAC RBAK RBPMS REEP6 REL RFT1 RNF6 SDCCAG8 SERTAD2 SH2B3 SHFL SOCS7 SORBS3 SPATA12 SPRY2 SPRY4 SUSD2 SUV39H1 TBC1D16 TCP10L TEKT3 TEKT5 TENT5A TENT5B TFAP2D TLE5 TM4SF19 TRIM8 TSC1 TWSG1 USP54 WAC WDFY3 ZCCHC14 ZIM2 ZNF134 ZNF205 ZNF250 ZNF417 ZNF497 ZNF575 ZNF586 ZNF587 ZNF648 ZNF655 ZNF688 ZNF837
Entrez ID		547	23371
HPRD ID		03156	16256
Ensembl ID		ENSG00000130294	ENSG00000111077
Uniprot IDs		A0A3B3IT28 A0A3B3ITE5 A0A3B3ITF7 A0A3B3ITK3 A0A3B3ITW6 A0A3B3IU40 A0A3B3IUA1 A0A3F2YNW9 C9JBH1 Q12756	Q63HR2
PDB IDs		4EGX 4EJQ 4UXO 4UXP 4UXR 4UXS 8UTN 8UTO 8UTP 8UTQ 8UTR 8UTS 8UTT 8UTU 8UTV 8UTW 8UTY	2DKQ 2KNO 2L6K 2LOZ 3HQC
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Communication Regulation Of Signaling Identical Protein Binding LBD Domain Binding Regulation Of Signal Transduction Nuclear Receptor-mediated Signaling Pathway Transcription Coregulator Binding Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of RNA Metabolic Process Nuclear Receptor Activity Cellular Response To Estrogen Stimulus Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Monocyte Differentiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Hormone-mediated Signaling Pathway Cytoplasm Nuclear Steroid Receptor Activity Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Transcription By RNA Polymerase II Mammary Gland Branching Involved In Pregnancy DNA Binding Domain Binding Positive Regulation Of Macromolecule Biosynthetic Process Zinc Ion Binding Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Lipoprotein Transport Negative Regulation Of Signal Transduction Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Cell Communication Negative Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Signaling Enzyme Binding MRNA Transcription By RNA Polymerase II Organ Growth Positive Regulation Of Signal Transduction Transcription Coactivator Binding Transcription Cis-regulatory Region Binding DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Prostate Gland Growth	Intermediate Filament Keratin Filament Protein Binding Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Receptor Complex Regulation Of RNA Metabolic Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Gene Expression Nucleus Enzyme-linked Receptor Protein Signaling Pathway Protein Tyrosine Kinase Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Basal Plasma Membrane Ruffle Membrane Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process ERBB2 Signaling Pathway Cell-substrate Adhesion Salivary Gland Morphogenesis ERBB3:ERBB2 Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Negative Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Macromolecule Metabolic Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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