TRIM42 and CEP70

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM42	CEP70
Gene Name		tripartite motif containing 42	centrosomal protein 70kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Membrane
	Molecular Function	Zinc Ion Binding	Protein Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		63 interactors: ADAMTSL4 ARMC7 ARNT2 ARRDC3 BEX2 C1orf109 CARD9 CCDC33 CCDC36 CDCA7L CEP70 EFHC2 EMD FAM103A1 FAM208B GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NL PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RCOR3 RUNX1T1 SCNM1 SPERT SSX2IP STK16 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1	134 interactors: ABT1 AKAP17A ARHGEF3 ATP5O ATXN7 BARD1 BEX2 BRMS1 BYSL C11orf57 C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CCDC94 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DIEXF DNAJB11 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B FAM64A GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NOL12 NOP2 NRIP1 NUSAP1 PAM16 PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RCOR3 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TCEB3 TCEB3B TEAD4 TRIM29 TRIM42 TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11L UTP14A ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF572 ZNF578 ZNF587 ZSCAN12
Entrez ID		287015	80321
HPRD ID		15559	16779
Ensembl ID		ENSG00000155890	ENSG00000114107
Uniprot IDs		Q8IWZ5	B7Z2D2 Q8NHQ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Apoptotic Process Cell Death Regulation Of Cell Death Death RNA Metabolic Process Transcription, DNA-templated Regulation Of Canonical Wnt Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Wnt Signaling Pathway Protein Polyubiquitination Regulation Of Signaling Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Viral Release From Host Cell Regulation Of Signal Transduction Apoptotic Process Negative Regulation Of Viral Process Positive Regulation Of Ligase Activity Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Cellular Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Gene Expression Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Protein Modification By Small Protein Conjugation Temperature Homeostasis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Protein K63-linked Ubiquitination Regulation Of Metabolic Process Protein Trimerization Positive Regulation Of Pro-T Cell Differentiation Abducens Nerve Formation Negative Regulation Of Locomotion Involved In Locomotory Behavior Optokinetic Behavior Negative Regulation Of Heat Generation Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Positive Regulation Of Protein Ubiquitination Positive Regulation Of Signal Transduction	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Ribonucleoprotein Complex Biogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process RRNA Processing Regulation Of Cellular Process RRNA Metabolic Process Ribosomal Small Subunit Biogenesis Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification MRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone H3-K9 Dimethylation RNA Processing Chromatin Organization Histone Modification Maturation Of SSU-rRNA Chromosome Organization Cell Death Death Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Apoptotic Process
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