TRIM42 and PTGER3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM42	PTGER3
Gene Name		tripartite motif containing 42	prostaglandin E receptor 3 (subtype EP3)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Zinc Ion Binding	Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Prostaglandin E Receptor Activity
	Biological Process		Fever Generation Transcription, DNA-templated G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Bicarbonate Transport Intracellular Receptor Signaling Pathway Positive Regulation Of Fever Generation Response To Lipopolysaccharide Positive Regulation Of Urine Volume
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Prostanoid ligand receptors GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Eicosanoid ligand-binding receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		63 interactors: ADAMTSL4 ARMC7 ARNT2 ARRDC3 BEX2 C1orf109 CARD9 CCDC33 CCDC36 CDCA7L CEP70 EFHC2 EMD FAM103A1 FAM208B GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NL PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RCOR3 RUNX1T1 SCNM1 SPERT SSX2IP STK16 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1	23 interactors: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NL PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42
Entrez ID		287015	5733
HPRD ID		15559	08906
Ensembl ID		ENSG00000155890	ENSG00000050628
Uniprot IDs		Q8IWZ5	B1AK19 O00325 P43115
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Apoptotic Process Cell Death Regulation Of Cell Death Death RNA Metabolic Process Transcription, DNA-templated Regulation Of Canonical Wnt Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Wnt Signaling Pathway Protein Polyubiquitination Regulation Of Signaling Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Viral Release From Host Cell Regulation Of Signal Transduction Apoptotic Process Negative Regulation Of Viral Process Positive Regulation Of Ligase Activity Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Cellular Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Gene Expression Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Protein Modification By Small Protein Conjugation Temperature Homeostasis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Protein K63-linked Ubiquitination Regulation Of Metabolic Process Protein Trimerization Positive Regulation Of Pro-T Cell Differentiation Abducens Nerve Formation Negative Regulation Of Locomotion Involved In Locomotory Behavior Optokinetic Behavior Negative Regulation Of Heat Generation Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Positive Regulation Of Protein Ubiquitination Positive Regulation Of Signal Transduction	Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Tagcloud ?			accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1
Tagcloud (Difference) ?			accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1
Tagcloud (Intersection) ?