TRIM42 and STK16

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM42	STK16
Gene Name		tripartite motif containing 42	serine/threonine kinase 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Cytoplasm Golgi-associated Vesicle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Serine/threonine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process		Regulation Of Signal Transduction Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autophosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		63 interactors: ADAMTSL4 ARMC7 ARNT2 ARRDC3 BEX2 C1orf109 CARD9 CCDC33 CCDC36 CDCA7L CEP70 EFHC2 EMD FAM103A1 FAM208B GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NL PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RCOR3 RUNX1T1 SCNM1 SPERT SSX2IP STK16 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1	47 interactors: ADAMTSL4 AES ALS2CR12 CALCOCO2 CCDC33 CRX CSNK2B DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FAM154A IKZF3 INCA1 KCTD14 KCTD17 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP26-1 MBP MEOX2 MGAT5B MIIP MTUS2 NAGK NIF3L1 NOTCH2NL PCSK5 PLSCR1 PLSCR3 REL RFX6 RPIA SKIL SPRY2 TCF12 TCF4 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6
Entrez ID		287015	8576
HPRD ID		15559	05281
Ensembl ID		ENSG00000155890	ENSG00000115661
Uniprot IDs		Q8IWZ5	O75716
PDB IDs			2BUJ
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Apoptotic Process Cell Death Regulation Of Cell Death Death RNA Metabolic Process Transcription, DNA-templated Regulation Of Canonical Wnt Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Wnt Signaling Pathway Protein Polyubiquitination Regulation Of Signaling Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Viral Release From Host Cell Regulation Of Signal Transduction Apoptotic Process Negative Regulation Of Viral Process Positive Regulation Of Ligase Activity Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Cellular Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Gene Expression Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Protein Modification By Small Protein Conjugation Temperature Homeostasis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Protein K63-linked Ubiquitination Regulation Of Metabolic Process Protein Trimerization Positive Regulation Of Pro-T Cell Differentiation Abducens Nerve Formation Negative Regulation Of Locomotion Involved In Locomotory Behavior Optokinetic Behavior Negative Regulation Of Heat Generation Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Positive Regulation Of Protein Ubiquitination Positive Regulation Of Signal Transduction	Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Immune System Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Cytokine Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Organic Substance Positive Regulation Of Cell Death Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Phospholipid Scrambling Regulation Of Nitrogen Compound Metabolic Process Gene Expression Positive Regulation Of Apoptotic Process Regulation Of Signaling Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Response To Stimulus Positive Regulation Of Signal Transduction Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Oligomerization Regulation Of Transcription, DNA-templated Negative Regulation Of Kinase Activity Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Protein Homooligomerization Developmental Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of RNA Metabolic Process Cell Death Death
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