BRICD5 and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		BRICD5	SYNE4
Description		BRICHOS domain containing 5	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Membrane	Nucleus Nuclear Envelope Nuclear Outer Membrane Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of Cell Population Proliferation	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		39 interacting genes: AQP6 ARL13B BIK CD69 CD79A CLEC2D CLRN1 CREB3L1 FKBP7 HHLA2 HSD17B13 ICAM3 IFNGR2 IFNLR1 KIR2DL3 KLRC1 LMNA LRRC25 LRRC4C MRM1 MTIF3 MUC1 NEMP1 PLEKHO1 PSCA PVR SCN3B SGPL1 SIGLEC9 SLAMF6 SLC18A1 SLC18A2 SORT1 SYNE4 TMEM234 TMEM248 TMEM79 TMPRSS2 TMX2	56 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CFTR CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250 ZNF648
Entrez ID		283870	163183
HPRD ID		14482	08776
Ensembl ID		ENSG00000182685	ENSG00000181392
Uniprot IDs		Q6PL45	Q8N205
PDB IDs			6R16 6WMD
Enriched GO Terms of Interacting Partners?		Membrane Aminergic Neurotransmitter Loading Into Synaptic Vesicle Serotonin:sodium:chloride Symporter Activity Monoamine:proton Antiporter Activity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Clathrin-sculpted Monoamine Transport Vesicle Membrane Positive Regulation Of Natural Killer Cell Mediated Immunity Neurotransmitter Loading Into Synaptic Vesicle External Side Of Plasma Membrane Serotonin Uptake Monoamine Transmembrane Transporter Activity Plasma Membrane Type III Interferon-mediated Signaling Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity Amine Transport Regulation Of Natural Killer Cell Mediated Immunity Serotonin Transport Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Trans-Golgi Network Transport Vesicle Carbohydrate Binding Protein Binding Neurotransmitter Reuptake Dopamine Transport	Protein Binding Bicellular Tight Junction Assembly Tight Junction Organization Tight Junction Assembly Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Apicolateral Plasma Membrane Regulation Of Glycogen (starch) Synthase Activity
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