BRICD5 and CD69

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BRICD5	CD69
Description		BRICHOS domain containing 5	CD69 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Membrane	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Molecular Sequestering Activity
	Biological Process	Regulation Of Cell Population Proliferation	Sphingosine-1-phosphate Receptor Signaling Pathway Cellular Response To Xenobiotic Stimulus T Cell Migration Negative Regulation Of T-helper 17 Cell Lineage Commitment Negative Regulation Of T Cell Migration
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)	Lymphocyte count ( 27863252 29403010 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 24076602) Neutrophil percentage of white cells ( 27863252 32888494) Type 1 diabetes ( 19430480 25751624) White blood cell count ( 32888494)
Interacting Genes		39 interacting genes: AQP6 ARL13B BIK CD69 CD79A CLEC2D CLRN1 CREB3L1 FKBP7 HHLA2 HSD17B13 ICAM3 IFNGR2 IFNLR1 KIR2DL3 KLRC1 LMNA LRRC25 LRRC4C MRM1 MTIF3 MUC1 NEMP1 PLEKHO1 PSCA PVR SCN3B SGPL1 SIGLEC9 SLAMF6 SLC18A1 SLC18A2 SORT1 SYNE4 TMEM234 TMEM248 TMEM79 TMPRSS2 TMX2	14 interacting genes: ATP6V0C BRICD5 CLDN1 EBP MAL NINJ2 PMP22 RPRM SLC35B2 SMARCB1 STRIT1 TMEM190 TSPO2 UPK1B
Entrez ID		283870	969
HPRD ID		14482	00119
Ensembl ID		ENSG00000182685	ENSG00000110848
Uniprot IDs		Q6PL45	Q07108 Q53ZX0
PDB IDs			1E87 1E8I 1FM5 3CCK 3HUP 8G94
Enriched GO Terms of Interacting Partners?		Membrane Aminergic Neurotransmitter Loading Into Synaptic Vesicle Serotonin:sodium:chloride Symporter Activity Monoamine:proton Antiporter Activity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Clathrin-sculpted Monoamine Transport Vesicle Membrane Positive Regulation Of Natural Killer Cell Mediated Immunity Neurotransmitter Loading Into Synaptic Vesicle External Side Of Plasma Membrane Serotonin Uptake Monoamine Transmembrane Transporter Activity Plasma Membrane Type III Interferon-mediated Signaling Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity Amine Transport Regulation Of Natural Killer Cell Mediated Immunity Serotonin Transport Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Trans-Golgi Network Transport Vesicle Carbohydrate Binding Protein Binding Neurotransmitter Reuptake Dopamine Transport	Membrane Protein Localization To Paranode Region Of Axon Cellular Developmental Process Protein Insertion Into Plasma Membrane Myelination Apical Plasma Membrane Axon Ensheathment Membrane Raft Polarization Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Membrane Destabilizing Activity Cholesterol Binding Compact Myelin Positive Regulation Of Glucose Mediated Signaling Pathway Germ Cell Nucleus Regulation Of Glucose Mediated Signaling Pathway Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Apical Plasma Membrane Urothelial Plaque Cellular Response To Butyrate Response To Butyrate Xenobiotic Transport Across Blood-nerve Barrier Cellular Response To Lead Ion Response To Interleukin-18 Establishment Of Blood-nerve Barrier Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Steroid Delta-isomerase Activity Cholestenol Delta-isomerase Activity Inner Acrosomal Membrane 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transport 5'-adenylyl Sulfate Transmembrane Transport 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction
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