KLHL20 and GMCL1

Number of citations of the paper that reports this interaction (PubMedID 26687681)
0

Data Source:
BioGRID (two hybrid)

		KLHL20	GMCL1
Description		kelch like family member 20	germ cell-less 1, spermatogenesis associated
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Cell Projection Perinuclear Region Of Cytoplasm	Nucleus Nuclear Matrix
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Type II Interferon Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding Identical Protein Binding
	Biological Process	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Ubiquitination	Germ Cell Development Spermatogenesis Cell Differentiation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Feeling miserable ( 29500382)	Atrial fibrillation ( 28416818 29892015 30061737) Colorectal or endometrial cancer ( 26621817) Red cell distribution width ( 32888494) Whole brain grey matter density ( 31530798)
Interacting Genes		81 interacting genes: ABLIM1 ACTA1 AOC1 ARHGAP10 ARHGEF11 ARHGEF12 ARHGEF19 ATG9A BCL6 BECN1 BEX1 BEX2 C1orf216 C21orf58 CASP8AP2 CC2D1A CEP126 CIDEC CIMIP1 CLCNKA COL8A1 CORO7 CRK CRMP1 DMAC2 DUSP21 ECT2 EIF3F ENKD1 EPAS1 ERG28 F13A1 FBLN1 FHL2 FIZ1 GBE1 GBP2 GMCL1 HR IVNS1ABP JMJD1C KLHL38 KLHL9 LMO2 LRIF1 LUC7L2 MESD MTNR1A NECAB3 NEDD9 NISCH NTAQ1 NUDCD3 NUP160 ORC4 PAPPA PDPK1 PGLS PIK3C3 PIN1 PML PNKD POLR3D PRKAG1 PRMT6 RACK1 RANBP3 RECK RFC2 SGTA SLC13A5 SLC3A2 STK16 SUV39H1 SVEP1 TFAP2D TNPO2 ULK1 USP20 VPS54 ZFAT	98 interacting genes: APLF APOL6 AXIN1 BEGAIN BSCL2 BYSL CCDC13 CCDC25 CDC37 CFAP298 CFAP410 CHIC2 CIB3 CLK2 CUL3 EHHADH ELOA EMD EXOC3 FAM50B FKBP1B FLYWCH1 FOSL2 FOXR1 FRMD6 GAGE1 GAGE10 GAGE12B GAGE12G GAGE12I GAGE12J GAGE2A GAGE2C GAGE2E GAGE5 GLRX3 GOLGA2 GRAMD1A HYKK IL17F KANK2 KAT5 KIFC3 KLHL20 KPNA2 KRT75 LNX1 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR MYLIP MYO5B NEBL NFIL3 NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PIBF1 PIH1D2 PPP1R18 PTPN7 QRICH1 RAD54B RANBP3 RASA1 RNF4 RNMT SHQ1 SLC15A3 SNX20 SPATA31J1 STK3 SUMO1 SUMO1P1 SYT17 SYT6 TBC1D1 TLK2 TMPO TRIM13 TRIM21 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 YY1 ZBTB24 ZMYM2 ZNF23 ZNF250
Entrez ID		27252	64395
HPRD ID		13918	13587
Ensembl ID		ENSG00000076321	ENSG00000087338
Uniprot IDs		Q9Y2M5	Q53SE7 Q96IK5
PDB IDs		5YQ4 6GY5 8CIA
Enriched GO Terms of Interacting Partners?		Protein Binding Midbody Phagophore Assembly Site Regulation Of Cytokinesis Cytoplasm Cellular Response To Glucose Starvation Phosphatidylinositol 3-kinase Complex, Class III, Type II Phosphatidylinositol 3-kinase Complex, Class III, Type I	Protein Binding Positive Regulation Of Viral Life Cycle Ubiquitin Protein Ligase Activity PML Body Protein Modification Process Regulation Of Viral Process Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Suppression Of Viral Release By Host Regulation Of Viral Transcription Negative Regulation Of Viral Transcription Transcription Factor Binding Protein Sumoylation Cytoplasm Post-translational Protein Modification Small Protein Activating Enzyme Binding Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Process Modification-dependent Protein Catabolic Process
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