KLHL20 and SLC13A5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KLHL20	SLC13A5
Description		kelch like family member 20	solute carrier family 13 member 5
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GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Cell Projection Perinuclear Region Of Cytoplasm	Nucleoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Type II Interferon Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Organic Acid:sodium Symporter Activity Protein Binding Citrate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Tricarboxylic Acid Transmembrane Transporter Activity Symporter Activity Solute:sodium Symporter Activity Sodium:dicarboxylate Symporter Activity Transmembrane Transporter Activity Identical Protein Binding
	Biological Process	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Ubiquitination	Monoatomic Ion Transport Sodium Ion Transport Tricarboxylic Acid Transport Oxaloacetate Transport Fumarate Transport Alpha-ketoglutarate Transport Succinate Transport Citrate Transport Tricarboxylic Acid Transmembrane Transport Sodium Ion Transmembrane Transport Transmembrane Transport Cellular Response To Lithium Ion Succinate Transmembrane Transport Organic Acid Transmembrane Transport
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	SLC-mediated transport of organic anions
Drugs
Diseases
GWAS		Feeling miserable ( 29500382)	Economic and political preferences (time) ( 22566634) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		81 interacting genes: ABLIM1 ACTA1 AOC1 ARHGAP10 ARHGEF11 ARHGEF12 ARHGEF19 ATG9A BCL6 BECN1 BEX1 BEX2 C1orf216 C21orf58 CASP8AP2 CC2D1A CEP126 CIDEC CIMIP1 CLCNKA COL8A1 CORO7 CRK CRMP1 DMAC2 DUSP21 ECT2 EIF3F ENKD1 EPAS1 ERG28 F13A1 FBLN1 FHL2 FIZ1 GBE1 GBP2 GMCL1 HR IVNS1ABP JMJD1C KLHL38 KLHL9 LMO2 LRIF1 LUC7L2 MESD MTNR1A NECAB3 NEDD9 NISCH NTAQ1 NUDCD3 NUP160 ORC4 PAPPA PDPK1 PGLS PIK3C3 PIN1 PML PNKD POLR3D PRKAG1 PRMT6 RACK1 RANBP3 RECK RFC2 SGTA SLC13A5 SLC3A2 STK16 SUV39H1 SVEP1 TFAP2D TNPO2 ULK1 USP20 VPS54 ZFAT	18 interacting genes: ADAMTSL4 CD79A CYSRT1 GJA8 GOLM1 KLHL20 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP5-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 MDFI
Entrez ID		27252	284111
HPRD ID		13918	10512
Ensembl ID		ENSG00000076321	ENSG00000141485
Uniprot IDs		Q9Y2M5	Q86YT5
PDB IDs		5YQ4 6GY5 8CIA	7JSJ 7JSK 8UVB 8UVH
Enriched GO Terms of Interacting Partners?		Protein Binding Midbody Phagophore Assembly Site Regulation Of Cytokinesis Cytoplasm Cellular Response To Glucose Starvation Phosphatidylinositol 3-kinase Complex, Class III, Type II Phosphatidylinositol 3-kinase Complex, Class III, Type I	Intermediate Filament Keratin Filament Identical Protein Binding Type II Interferon Binding Pigment Cell Development
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