PDCD4 and PSEN2

  • Number of citations of the paper that reports this interaction (PMID 21163940)
  • 13
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

PDCD4

PSEN2

Gene Name programmed cell death 4 (neoplastic transformation inhibitor) presenilin 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 12 interactors: APOE BTRC CSNK2A1 EIF4A2 EIF4A3 EIF4G1 PSEN1 PSEN2 RPL5 RPLP1 RPS13 RPS6KA1 58 interactors: AAMP ACTG1 APH1A APH1B APP BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B MGEA5 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1
Entrez ID 27250 5664
HPRD ID 10549 02860
Ensembl ID ENSG00000150593 ENSG00000143801
Uniprot IDs B4DKX4 Q53EL6 P49810
PDB IDs 2GGF 2KZT 2RG8 2ZU6 3EIJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
classes  constituents  cycling  cyclins  dexd  dysregulation  eif4a  eif4a1  eif4b  eif4e  helicase  helicases  impede  mcf7  microrna  motors  oncogenic  otherwise  pcdc4  polysome  preferential  quadruplexes  ribosome  structured  translatome  ubiquitous  unwind  unwinding  utrs 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Difference) ?
classes  constituents  cycling  cyclins  dexd  dysregulation  eif4a  eif4a1  eif4b  eif4e  helicase  helicases  impede  mcf7  microrna  motors  oncogenic  otherwise  pcdc4  polysome  preferential  quadruplexes  ribosome  structured  translatome  ubiquitous  unwind  unwinding  utrs 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Intersection) ?