SPTAN1 and ACP1

Number of citations of the paper that reports this interaction (PMID 11971983)
19

Data Source:
HPRD (in vitro, two hybrid)

		SPTAN1	ACP1
Gene Name		spectrin, alpha, non-erythrocytic 1	acid phosphatase 1, soluble
Image
Gene Ontology Annotations	Cellular Component	Cytosol Fascia Adherens Spectrin Microtubule Cytoskeleton Membrane Lateral Plasma Membrane Z Disc Vesicle Cuticular Plate Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Cytoplasm Cytoplasmic Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Calmodulin Binding Spectrin Binding Protein Heterodimerization Activity	Acid Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Axon Guidance Actin Filament Capping	Peptidyl-tyrosine Dephosphorylation
Pathways		Interaction between L1 and Ankyrins Apoptotic cleavage of cellular proteins Axon guidance Programmed Cell Death Apoptotic execution phase Nephrin interactions L1CAM interactions Caspase-mediated cleavage of cytoskeletal proteins NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ABI1 ABL1 ACP1 ACTA1 ACTB ADD1 ANK1 CAPN1 CASP3 CASP7 CEP63 CTNNA1 DDX24 DES DISC1 EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D MAPK6 NEFL PIN4 PLEC PLEKHA5 PRKCB PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SRC STAT1 SYN1 TANC1 TES TSSC4	15 interactors: BARD1 CTNNB1 EPHA2 EPHB1 EPHB2 FABP4 FNBP1L FYN INSR KDR LCK MRPL20 SFMBT1 SPTAN1 ZAP70
Entrez ID		6709	52
HPRD ID		01684	08881
Ensembl ID		ENSG00000197694	ENSG00000143727
Uniprot IDs		Q13813	B5MCC7 P24666 Q59EH3
PDB IDs		2FOT 3F31 3FB2	1XWW 3N8I 5PNT
Enriched GO Terms of Interacting Partners?		Cell Morphogenesis Neuron Projection Morphogenesis Neuron Projection Development Cell Projection Organization Axon Development Cell Projection Morphogenesis Cell Development Cell Part Morphogenesis Cell Morphogenesis Involved In Differentiation Cell Morphogenesis Involved In Neuron Differentiation Cytoskeleton Organization Neuron Differentiation Neuron Development Axon Guidance Cell Differentiation Neurogenesis Anatomical Structure Morphogenesis Generation Of Neurons Axonogenesis Neuromuscular Process Movement Of Cell Or Subcellular Component Ionotropic Glutamate Receptor Signaling Pathway Chemotaxis Organelle Organization System Development Synaptic Transmission, Glutamatergic Response To External Stimulus Anatomical Structure Development Homeostatic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Locomotion Glutamate Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Nervous System Development Membrane Depolarization Synaptic Transmission Neuron-neuron Synaptic Transmission Cellular Component Assembly Startle Response Actin Filament-based Process Developmental Process Regulation Of Excitatory Postsynaptic Membrane Potential Learning Multicellular Organismal Development Regulation Of Postsynaptic Membrane Potential Signaling Response To Wounding Cell Communication Cellular Response To Stimulus	Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Protein Autophosphorylation Movement Of Cell Or Subcellular Component Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Locomotion Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-amino Acid Modification Ephrin Receptor Signaling Pathway Cell Migration Developmental Process Regulation Of Phosphorylation Protein Phosphorylation Cell Differentiation Regulation Of Cellular Component Organization Cell Motility Camera-type Eye Morphogenesis Regulation Of Phosphorus Metabolic Process Response To Growth Factor Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Adhesion Angiogenesis Cell Morphogenesis Eye Morphogenesis Cell Morphogenesis Involved In Differentiation Axon Guidance Anatomical Structure Morphogenesis Regulation Of Intracellular Signal Transduction Blood Vessel Morphogenesis Phosphorylation Positive Regulation Of Intracellular Signal Transduction Optic Nerve Morphogenesis Cell Projection Morphogenesis Positive Regulation Of Cell Differentiation Cell Part Morphogenesis Cardiovascular System Development Dendrite Morphogenesis Blood Vessel Development Axonogenesis Vasculature Development Dendritic Spine Morphogenesis Viral Process Anatomical Structure Development Organ Development Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation T Cell Aggregation T Cell Activation Optic Nerve Development
Tagcloud ?		adenocarcinomas atxn2 biology consistently couple deregulation dhx9 driver exome hundreds kras mutations myof never overlap preferentially ptpn13 recurrent respective rps6kb2 seq sequenced smokers somatic sp1 stratification targetable ten thousands	ada ada2 additive adenosine allele approved cad carriers codon committee consent contribution deaminase diabetic donors ethical functionally give hints informed multifactorial note phosphatse proportion ptpn22 simultaneous strength stresses written
Tagcloud (Difference) ?		adenocarcinomas atxn2 biology consistently couple deregulation dhx9 driver exome hundreds kras mutations myof never overlap preferentially ptpn13 recurrent respective rps6kb2 seq sequenced smokers somatic sp1 stratification targetable ten thousands	ada ada2 additive adenosine allele approved cad carriers codon committee consent contribution deaminase diabetic donors ethical functionally give hints informed multifactorial note phosphatse proportion ptpn22 simultaneous strength stresses written
Tagcloud (Intersection) ?