LAT and GAB2

  • Number of citations of the paper that reports this interaction (PMID 11572860)
  • 16
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

LAT

GAB2

Gene Name linker for activation of T cells GRB2-associated binding protein 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 17553421)
  • Menarche (age at onset) ( 21102462)
Protein-Protein Interactions 28 interactors: CBL CD244 CD4 CD8A FCGR1A FCGR2A FYN GAB2 GRAP GRAP2 GRB2 ITK LCK LCP2 MAP4K1 PIK3R1 PLCG1 PLCG2 PTPN1 PTPRJ SGTA SH3BP2 SHB SLA SYK VAV1 ZAP70 ZHX2 28 interactors: AKT1 ARHGAP32 CD247 CRKL EPOR ETV6 GAB1 GRAP GRAP2 GRB2 INPP5D LAT LCK LYN MAPK1 MAPK3 MAPK4 NCK1 PIK3R1 PLCG1 PLCG2 PTPN11 PTPN6 SHC1 SRC SYK TNFRSF11A ZAP70
Entrez ID 27040 9846
HPRD ID 03832 05866
Ensembl ID ENSG00000213658 ENSG00000033327
Uniprot IDs B7WPI0 G5E9K3 O43561 Q9UQC2
PDB IDs 2VWF 2W0Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abolish  acting  amp  beginning  besides  box  contributed  cre  deleting  element  elements  exciting  extension  full  herpes  initiator  lap1  latency  latently  lats  positioned  primer  simplex  start  substitution  tata  true  unexplored  usf 
adaptor  adenocarcinomas  compensate  contribution  deletion  demonstrating  driven  egfr  egfrl858r  erbb2  erbb3  gab1  inducible  initiate  inositol  member  met  mutant  observations  phosphatidyl  pi3k  plasticity  remarkable  retained  tamoxifen  tetracycline  tkis  tumorigenesis 
Tagcloud (Difference) ?
abolish  acting  amp  beginning  besides  box  contributed  cre  deleting  element  elements  exciting  extension  full  herpes  initiator  lap1  latency  latently  lats  positioned  primer  simplex  start  substitution  tata  true  unexplored  usf 
adaptor  adenocarcinomas  compensate  contribution  deletion  demonstrating  driven  egfr  egfrl858r  erbb2  erbb3  gab1  inducible  initiate  inositol  member  met  mutant  observations  phosphatidyl  pi3k  plasticity  remarkable  retained  tamoxifen  tetracycline  tkis  tumorigenesis 
Tagcloud (Intersection) ?