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LAT
Gene Name
linker for activation of T cells
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Immunological Synapse
Plasma Membrane
Cell-cell Junction
COP9 Signalosome
Integral Component Of Membrane
Mast Cell Granule
Membrane Raft
Molecular Function
SH3/SH2 Adaptor Activity
Protein Binding
Protein Kinase Binding
Biological Process
Lymphocyte Homeostasis
Inflammatory Response
Immune Response
Integrin-mediated Signaling Pathway
Ras Protein Signal Transduction
Blood Coagulation
Positive Regulation Of Signal Transduction
Gene Expression
Calcium-mediated Signaling
Platelet Activation
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
T Cell Activation
Mast Cell Degranulation
Innate Immune Response
T Cell Receptor Signaling Pathway
Regulation Of T Cell Activation
Pathways
TCR signaling
Generation of second messenger molecules
GPVI-mediated activation cascade
Platelet activation, signaling and aggregation
Adaptive Immune System
Drugs
Diseases
GWAS
Crohn's disease (
21102463
)
Protein-protein Interactions
28 interactors:
CBL
CD244
CD4
CD8A
FCGR1A
FCGR2A
FYN
GAB2
GRAP
GRAP2
GRB2
ITK
LCK
LCP2
MAP4K1
PIK3R1
PLCG1
PLCG2
PTPN1
PTPRJ
SGTA
SH3BP2
SHB
SLA
SYK
VAV1
ZAP70
ZHX2
Entrez ID
27040
HPRD ID
03832
Ensembl ID
ENSG00000213658
Uniprot IDs
B7WPI0
G5E9K3
O43561
PDB IDs
Enriched GO Terms of Interacting Partners
?
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Immune Response
Positive Regulation Of Immune Response
Innate Immune Response
Antigen Receptor-mediated Signaling Pathway
Regulation Of Immune System Process
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Immune System Process
Fc-epsilon Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Immune Response
Defense Response
Positive Regulation Of Cell Activation
Blood Coagulation
Hemostasis
Immune System Process
Signal Transduction
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Cell Surface Receptor Signaling Pathway
Cell Activation
Regulation Of Signal Transduction
Signaling
Cell Communication
Platelet Activation
Regulation Of Body Fluid Levels
Response To Stress
Wound Healing
Positive Regulation Of T Cell Activation
Regulation Of Signaling
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Cell Activation
Leukocyte Activation
T Cell Costimulation
Leukocyte Migration
Positive Regulation Of Cell-cell Adhesion
Response To Wounding
Positive Regulation Of Cell Adhesion
Phagocytosis
Lymphocyte Activation
Cellular Response To Stimulus
Intracellular Signal Transduction
Regulation Of T Cell Activation
Leukocyte Differentiation
Tagcloud
?
abolish
acting
amp
beginning
besides
box
contributed
cre
deleting
element
elements
exciting
extension
full
herpes
initiator
lap1
latency
latently
lats
positioned
primer
simplex
start
substitution
tata
true
unexplored
usf