GAB2 and PLCG1

  • Number of citations of the paper that reports this interaction (PMID 10391903)
  • 29

GAB2

PLCG1

Gene Name GRB2-associated binding protein 2 phospholipase C, gamma 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 17553421)
  • Menarche (age at onset) ( 21102462)
Protein-Protein Interactions 28 interactors: AKT1 ARHGAP32 CD247 CRKL EPOR ETV6 GAB1 GRAP GRAP2 GRB2 INPP5D LAT LCK LYN MAPK1 MAPK3 MAPK4 NCK1 PIK3R1 PLCG1 PLCG2 PTPN11 PTPN6 SHC1 SRC SYK TNFRSF11A ZAP70 106 interactors: ABL1 AGAP2 AGTR1 AKT1 ALK ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GNB2L1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PTK2 PTPN11 PTPRJ RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70
Entrez ID 9846 5335
HPRD ID 05866 01398
Ensembl ID ENSG00000033327 ENSG00000124181
Uniprot IDs Q9UQC2 P19174 Q4LE43 Q9UFY1
PDB IDs 2VWF 2W0Z 1HSQ 2HSP 4EY0 4FBN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adaptor  adenocarcinomas  compensate  contribution  deletion  demonstrating  driven  egfr  egfrl858r  erbb2  erbb3  gab1  inducible  initiate  inositol  member  met  mutant  observations  phosphatidyl  pi3k  plasticity  remarkable  retained  tamoxifen  tetracycline  tkis  tumorigenesis 
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
Tagcloud (Difference) ?
adaptor  adenocarcinomas  compensate  contribution  deletion  demonstrating  driven  egfr  egfrl858r  erbb2  erbb3  gab1  inducible  initiate  inositol  met  mutant  observations  phosphatidyl  pi3k  plasticity  remarkable  retained  tamoxifen  tetracycline  tkis  tumorigenesis 
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
Tagcloud (Intersection) ?
member