GBP2 and SAT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GBP2	SAT1
Description		guanylate binding protein 2	spermidine/spermine N1-acetyltransferase 1
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GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding GTPase Activity Endopeptidase Inhibitor Activity Protein Binding GTP Binding Hydrolase Activity Identical Protein Binding Protein Homodimerization Activity Molecular Function Inhibitor Activity	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Spermidine Binding Identical Protein Binding
	Biological Process	Activation Of Innate Immune Response Immune System Process Immune Response Protein Localization To Nucleus Defense Response To Bacterium Defense Response To Protozoan Innate Immune Response Symbiont Entry Into Host Cell Defense Response To Gram-positive Bacterium Protein Maturation Defense Response To Virus Cytolysis In Another Organism Cellular Response To Lipopolysaccharide Cellular Response To Type II Interferon Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Pyroptotic Inflammatory Response Positive Regulation Of AIM2 Inflammasome Complex Assembly	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Regulation Of Cell Population Proliferation
Pathways		Interferon gamma signaling Interferon alpha/beta signaling CASP4 inflammasome assembly Microbial factors inhibit CASP4 activity	Interconversion of polyamines
Drugs			N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases			Keratosis follicularis spinulosa decalvans
GWAS		Serum metabolite levels ( 33031748)	Shoulder impingement or rotator cuff tear ( 33482370)
Interacting Genes		22 interacting genes: ANXA7 BID BNIP3L BTBD2 CSNK2B FBXO7 FXR1 GADD45A GSK3B HSPE1 KLHL20 LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG	98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 SPMIP10 TACO1 TCF25 TEAD4 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1
Entrez ID		2634	6303
HPRD ID		02682	02431
Ensembl ID		ENSG00000162645	ENSG00000130066
Uniprot IDs		P32456 Q8TCE5	A0A384NQ10 P21673
PDB IDs		6VKJ 7E58 7M1S	2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?		Cytoplasm Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Membrane Permeability Positive Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Mitochondrial Membrane Permeability Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Intracellular Signal Transduction Protein Heterodimerization Activity Regulation Of Membrane Permeability Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Signaling Pathway Protein-containing Complex Assembly Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Hepatocyte Apoptotic Process Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Apoptotic Signaling Pathway Protein-containing Complex Organization Mitochondrial Membrane Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Catabolic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Protein Targeting To Mitochondrion Positive Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Extrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Negative Regulation Of Proteolysis Protein Phosphorylation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of JNK Cascade Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Microtubule Anchoring At Centrosome Cytoplasmic Translational Initiation Ribonuclease E Activity Spermidine Binding Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Type II Interferon Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Autophagy Phosphorylation	Protein Binding Chromatin
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