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GBP2 and FXR1
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
GBP2
FXR1
Description
guanylate binding protein 2
FMR1 autosomal homolog 1
Image
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Membrane
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Perinuclear Region Of Cytoplasm
Nucleus
Nuclear Envelope
Nucleolus
Cytoplasm
Cytosol
Ribosome
Cytoplasmic Stress Granule
Membrane
Axon
Dendrite
Ribonucleoprotein Granule
Cytoplasmic Ribonucleoprotein Granule
Cell Projection
Neuron Projection
Costamere
Dendritic Spine
Intracellular Membraneless Organelle
Synapse
Perinuclear Region Of Cytoplasm
Presynapse
Postsynapse
Glutamatergic Synapse
Molecular Function
Nucleotide Binding
GTPase Activity
Endopeptidase Inhibitor Activity
Protein Binding
GTP Binding
Hydrolase Activity
Identical Protein Binding
Protein Homodimerization Activity
Molecular Function Inhibitor Activity
Nucleic Acid Binding
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
RNA Strand Annealing Activity
MRNA 3'-UTR AU-rich Region Binding
Protein Homodimerization Activity
Ribonucleoprotein Complex Binding
Translation Regulator Activity
Protein Heterodimerization Activity
Molecular Condensate Scaffold Activity
Biological Process
Activation Of Innate Immune Response
Immune System Process
Immune Response
Protein Localization To Nucleus
Defense Response To Bacterium
Defense Response To Protozoan
Innate Immune Response
Symbiont Entry Into Host Cell
Defense Response To Gram-positive Bacterium
Protein Maturation
Defense Response To Virus
Cytolysis In Another Organism
Cellular Response To Lipopolysaccharide
Cellular Response To Type II Interferon
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Pyroptotic Inflammatory Response
Positive Regulation Of AIM2 Inflammasome Complex Assembly
Cytoplasmic Translational Initiation
Regulation Of Translation
Apoptotic Process
Spermatogenesis
Spermatid Development
Muscle Organ Development
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Translation
Dentate Gyrus Development
Cell Differentiation
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Rho Protein Signal Transduction
Regulation Of MRNA Stability
Regulation Of Circadian Sleep/wake Cycle, Sleep
Positive Regulation Of Translation
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Animal Organ Development
Negative Regulation Of Inflammatory Response
Regulation Of Neurogenesis
MRNA Transport
Nuclear Pore Complex Assembly
Nuclear Pore Localization
Regulation Of Synaptic Transmission, Glutamatergic
Skeletal Muscle Organ Development
Muscle Structure Development
MRNA Destabilization
Regulation Of Translation At Presynapse, Modulating Synaptic Transmission
Membraneless Organelle Assembly
Negative Regulation Of Long-term Synaptic Potentiation
Negative Regulation Of MRNA Catabolic Process
Positive Regulation Of MiRNA-mediated Gene Silencing
Pathways
Interferon gamma signaling
Interferon alpha/beta signaling
CASP4 inflammasome assembly
Microbial factors inhibit CASP4 activity
Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS
Serum metabolite levels (
33031748
)
Bipolar disorder and eating disorder (
26433762
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Eating disorder in bipolar disorder (
26433762
)
Mastocytosis (
32752121
)
Metabolite levels (
23823483
)
Schizophrenia (
19571811
25056061
29483656
30285260
)
Interacting Genes
22 interacting genes:
ANXA7
BID
BNIP3L
BTBD2
CSNK2B
FBXO7
FXR1
GADD45A
GSK3B
HSPE1
KLHL20
LSM2
MAGI1
MAPK8IP2
PAFAH1B3
PPP1R8
RPS6KA1
SAT1
SEPHS1
SERPINB9
STK3
TFG
254 interacting genes:
ABI1
ACLY
ACOT7
ACTB
ACTN1
ACTN2
ADAMTSL4
AHCY
ALAS1
ANKRD40
ANKS3
AP1M1
APC2
ARHGAP22
ARHGEF7
ATN1
AXIN1
AXIN2
BCKDK
BEND5
BHLHE40
BICD1
BLK
BLTP3B
BTBD2
BTBD6
BYSL
C1orf35
CA10
CACTIN-AS1
CALCOCO1
CAMK2A
CAMK2B
CAMK2G
CAPN3
CBS
CBX8
CCAR2
CCBE1
CCDC187
CCDC92
CCN3
CDC7
CDKL3
CDR2
CDYL
CEP126
CEP72
CEP89
CHRD
CIRSR
COIL
CORO1A
CORO1B
CORO6
CPLANE1
CRMP1
CSNK2A1
CSNK2B
CWF19L2
CYFIP2
DCTD
DCTN1
DCTN2
DCTPP1
DEAF1
DHX15
DNAJA3
DNM2
ECH1
ECHS1
ECM1
EDC4
EFEMP2
EGFL7
EIF3A
ELOA
ENO1
ERCC6
ERG28
ERVFRD-1
ESCO2
EVL
FAM161A
FAM90A1
FBLN1
FLAD1
FLNB
FMR1
FTH1
FXR2
GBP2
GFAP
GLYR1
GOLGA2
GOLGA3
GPSM2
GRIA2
GRIP1
GRIP2
GRIPAP1
HIVEP1
HLA-DRB5
HMG20A
HNRNPH2
HNRNPM
HNRNPUL1
HOMER2
HOMER3
HSPB1
IK
IMPDH2
INA
JAKMIP1
KAZN
KCNN1
KCTD1
KCTD13
KEAP1
KHDRBS1
KHDRBS3
KIAA1549L
KIF17
KIF9
KRT18
LAP3
LNX1
LRIF1
LRSAM1
LUC7L2
LZTS2
MAD1L1
MAGED1
MAGOH
MAGOHB
MAPK7
MAPK8IP3
MAPKBP1
MBIP
MCRS1
MFAP1
MLLT1
MOAP1
MSANTD3
MTUS2
MVP
MX1
MYH10
MYH9
MYO5B
N4BP3
NBPF15
NECAB2
NECAB3
NEFL
NEIL3
NKD2
NME1
NME1-NME2
NME3
PAFAH1B3
PAICS
PCCB
PCED1A
PDE9A
PHC1P1
PHC2
PHLDB1
PKM
PML
PNMA1
PPHLN1
PPP1R12C
PRAM1
PRKCSH
PRPF31
PRR13
PRSS23
PSMC3
PSMC5
PSME1
PSME3
PYCR1
PYCR2
PYCR3
RABAC1
RALYL
RBM26
RBM45
RPIA
RUSC2
SAFB2
SAMD1
SCMH1
SEPTIN2
SERTAD1
SF3B2
SFPQ
SH3GL2
SH3GLB2
SHANK1
SHARPIN
SLC48A1
SLIT1
SMN1
SNURF
SORBS3
SOX5
SPECC1
SPRY1
SPRY2
SRPK2
SSNA1
STK16
STUB1
SUFU
SYT6
TACC2
TASOR2
TBC1D22B
TCEA2
TDRD7
TLE5
TMPO
TNFAIP1
TRAF2
TRAP1
TRIM3
TRIOBP
TRPM1
TSN
TTLL5
TUBB
UBAP2L
UBP1
USP7
UXS1
VIM
VPS51
VWF
WASH6P
WEE2-AS1
WRNIP1
YAP1
YES1
YY1AP1
ZFTRAF1
ZMAT2
ZNF212
ZNF417
ZNF423
ZNF438
ZNF71
ZNF821
Entrez ID
2634
8087
HPRD ID
02682
02892
Ensembl ID
ENSG00000162645
ENSG00000114416
Uniprot IDs
P32456
Q8TCE5
E7EU85
P51114
PDB IDs
6VKJ
7E58
7M1S
2CPQ
3KUF
3O8V
Enriched GO Terms of Interacting Partners
?
Cytoplasm
Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Membrane Permeability
Positive Regulation Of Mitochondrial Membrane Permeability
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Mitochondrial Membrane Permeability
Mitochondrial Outer Membrane Permeabilization
Positive Regulation Of Intracellular Signal Transduction
Protein Heterodimerization Activity
Regulation Of Membrane Permeability
Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Signaling Pathway
Protein-containing Complex Assembly
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Hepatocyte Apoptotic Process
Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death
Negative Regulation Of Apoptotic Signaling Pathway
Protein-containing Complex Organization
Mitochondrial Membrane Organization
Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Catabolic Process
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Process
Protein Targeting To Mitochondrion
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Signal Transduction
Regulation Of Extrinsic Apoptotic Signaling Pathway
Apoptotic Signaling Pathway
Negative Regulation Of Proteolysis
Protein Phosphorylation
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Catalytic Activity
Regulation Of JNK Cascade
Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein
Presynaptic Modulation Of Chemical Synaptic Transmission
Regulation Of Microtubule Anchoring At Centrosome
Cytoplasmic Translational Initiation
Ribonuclease E Activity
Spermidine Binding
Glial Cytoplasmic Inclusion
Classical Lewy Body
Lewy Body Corona
Lewy Neurite
Type II Interferon Binding
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Positive Regulation Of Autophagy
Phosphorylation
Identical Protein Binding
Cytosol
Cytoplasm
Cytoskeleton
Protein Binding
Regulation Of Proteolysis
Cytoskeleton Organization
Postsynaptic Cytoskeleton Organization
Centrosome
Nucleoplasm
Protein Domain Specific Binding
Regulation Of Proteasomal Protein Catabolic Process
Symbiont-mediated Disruption Of Host Cell PML Body
Pyrroline-5-carboxylate Reductase Activity
Nucleus
Neuron Projection
Actin Filament
Organelle Organization
Synapse
Positive Regulation Of Proteolysis
Mitotic Spindle Pole
RNA Splicing, Via Transesterification Reactions
Calcium- And Calmodulin-dependent Protein Kinase Complex
Regulation Of Protein Metabolic Process
L-proline Biosynthetic Process
RNA Splicing
PcG Protein Complex
MRNA Processing
Stress Fiber
MRNA Splicing, Via Spliceosome
Microtubule Cytoskeleton Organization
Supramolecular Fiber Organization
Nervous System Development
Postsynaptic Actin Cytoskeleton Organization
Protein Homodimerization Activity
Regulation Of Ubiquitin-dependent Protein Catabolic Process
DNA Protection
Cell Cortex
U2-type Precatalytic Spliceosome
Bud Elongation Involved In Lung Branching
Glutamate Receptor Signaling Pathway
Structural Constituent Of Cytoskeleton
Postsynaptic Density
Microtubule Binding
Crotonyl-CoA Hydratase Activity
Uropod Organization
Protein Kinase Binding
RNA Binding
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
GTP Biosynthetic Process
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Tagcloud (Difference)
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Tagcloud (Intersection)
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