APPL1 and DPYSL5

  • Number of citations of the paper that reports this interaction (PMID 21988832)
  • 14
  • Data Source:
  • BioGRID (two hybrid)

APPL1

DPYSL5

Gene Name adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 dihydropyrimidinase-like 5
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Fasting glucose-related traits (interaction with BMI) ( 22581228)
  • Obesity-related traits ( 23251661)
Protein-Protein Interactions 25 interactors: ADIPOR1 AKT1 AKT2 APPL2 CMTM4 DCC DPYSL5 EGFR FARS2 FSHR HDAC1 HDAC2 KXD1 MAGEA9 MEOX1 MTA2 PIK3CA PLEKHF2 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 TRAF2 UBE2O 8 interactors: APPL1 DARS2 DPYS DPYSL2 DPYSL3 DPYSL4 FES HSPA5
Entrez ID 26060 56896
HPRD ID 05053 10522
Ensembl ID ENSG00000157500 ENSG00000157851
Uniprot IDs Q9UKG1 Q9BPU6
PDB IDs 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O 4B90 4B91 4B92
Enriched GO Terms of Interacting Partners?
Tagcloud ?
characterised  colocalisation  colocalises  compartments  eea1  employ  endocytic  endosome  endosomes  engages  entered  escrt  gradually  intermediates  intralumenal  labelled  localise  localises  move  snx15  solely  sorts  subpixel  suite  transit  transporting  ubiquitinated  vacuolar  whilst 
Tagcloud (Difference) ?
characterised  colocalisation  colocalises  compartments  eea1  employ  endocytic  endosome  endosomes  engages  entered  escrt  gradually  intermediates  intralumenal  labelled  localise  localises  move  snx15  solely  sorts  subpixel  suite  transit  transporting  ubiquitinated  vacuolar  whilst 
Tagcloud (Intersection) ?