PDE9A and BAG3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PDE9A	BAG3
Gene Name		phosphodiesterase 9A	BCL2-associated athanogene 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Cytosol Ruffle Membrane Perikaryon Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Plasma Membrane Z Disc Neuron Projection
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Protein Binding Protein Complex Binding Chaperone Binding
	Biological Process	Signal Transduction Blood Coagulation Metabolic Process CGMP-mediated Signaling	Protein Folding Brain Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Striated Muscle Cell Apoptotic Process Spinal Cord Development Negative Regulation Of Apoptotic Process Protein Stabilization Cellular Response To Mechanical Stimulus Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Platelet homeostasis Nitric oxide stimulates guanylate cyclase cGMP effects
Drugs
Diseases
GWAS			Dilated cardiomyopathy ( 21459883)
Protein-Protein Interactions		18 interactors: BAG3 C9orf106 CLK1 CRY2 GORASP2 KRTAP10-3 KRTAP10-8 KRTAP4-2 KRTAP9-2 LAGE3 LMO2 NAA38 NOTCH2NL PHYHIPL SULT1E1 TRIM32 TRPV6 UTP23	20 interactors: ACD ARRDC3 BCL2 CRYAB DAZAP2 DVL2 DYNLT1 FAM189A2 HSPA1A HSPA8 HSPB8 LITAF MAGED1 PDE9A PLCG1 POT1 SF3B4 TINF2 TNK2 WNK1
Entrez ID		5152	9531
HPRD ID		09115	04860
Ensembl ID		ENSG00000160191	ENSG00000151929
Uniprot IDs		O76083	O95817
PDB IDs		2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6
Enriched GO Terms of Interacting Partners?			Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Catalytic Activity Regulation Of Telomere Maintenance Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Cellular Component Organization Negative Regulation Of DNA Replication Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Positive Regulation Of Protein Modification Process Negative Regulation Of DNA Metabolic Process Regulation Of Telomerase Activity Negative Regulation Of Intracellular Transport Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Catalytic Activity Positive Regulation Of DNA Biosynthetic Process Protein Refolding Regulation Of Protein Phosphorylation Regulation Of DNA Replication Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of DNA Metabolic Process Positive Regulation Of RNA Splicing Negative Regulation Of Cell Growth Negative Regulation Of Transport Regulation Of Glycoprotein Biosynthetic Process Protein Localization To Chromosome Regulation Of Cellular Response To Heat Positive Regulation Of Protein Metabolic Process Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Positive Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Cellular Process Regulation Of Phosphorylation Regulation Of Organ Morphogenesis Positive Regulation Of Phosphorylation
Tagcloud ?		acetylcholinesterase adas aes cgi cgmp cog cognition diarrhea discontinuation elevates guanoscine impression memantine mini mmse monophosphate nausea neuropsychiatric npi overexpress pf pharmacokinetics phosphodiesterase placebo probable q12h subscale tg2576	athanogene bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Difference) ?		acetylcholinesterase adas aes cgi cgmp cog cognition diarrhea discontinuation elevates guanoscine impression memantine mini mmse monophosphate nausea neuropsychiatric npi overexpress pf pharmacokinetics phosphodiesterase placebo probable q12h subscale tg2576	athanogene bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Intersection) ?