ARFIP2 and TRIM54

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ARFIP2	TRIM54
Gene Name		ADP-ribosylation factor interacting protein 2	tripartite motif containing 54
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Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Plasma Membrane Cell Cortex Trans-Golgi Network Membrane	Microtubule Microtubule Associated Complex Z Disc
	Molecular Function	Protein Binding GTP Binding Protein Domain Specific Binding GTP-dependent Protein Binding Rac GTPase Binding Phosphatidylinositol-4-phosphate Binding	Signal Transducer Activity Microtubule Binding Zinc Ion Binding
	Biological Process	Movement Of Cell Or Subcellular Component Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization	Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Signal Transduction Multicellular Organismal Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARL1 CDKN2A CEP63 DTNBP1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 LY6D MAL2 RAC1 RAC2 SNX1 SOCS2 STAT3 TRIM54 USHBP1	127 interactors: ADCY4 ALS2CR11 ARFIP2 ARHGEF5 ATXN3 ATXN3L ATXN7 BYSL C12orf49 C1orf109 C1orf216 C1QTNF2 CALM3 CARD9 CCDC102B CCDC146 CCDC28A CCDC67 CCDC87 CDK18 CDKN1A CEP57L1 CHCHD2 CKM CRADD CWF19L2 CYTH4 DCUN1D1 DNAL4 DTX2 EHHADH EIF4E2 ELMO1 ENKD1 EPM2AIP1 EXOSC5 FAM110A FAM124A FAM124B FAM161A FARS2 FBF1 FLNC GEM GMCL1 GTF2IRD2 HAUS1 ING3 INPP5J IQUB JOSD1 KDM1A KIFC3 KLHL38 KPNA2 KRT6A KRT6B KRT6C LENG1 LIN37 LMO2 LNX1 LSM2 MAPK3 MBD3 MCM7 MEAF6 MFAP1 MID2 MYO5B NGLY1 OSTF1 OTUB1 OTUB2 PIK3R3 PPP1R18 PRF1 RABGEF1 RAD23A RBM41 RCOR3 RSRC2 SCNM1 SDCBP SENP3 SH2D1B SMARCE1 SNF8 SPG21 SSX2IP STAM STRA13 TBC1D22B TCEA2 TCEB3 THOC1 TRIM55 TRIM63 TSHZ3 TTC23 UBE2D3 UBE2I UBE2U UCHL1 UCHL3 UCHL5 USHBP1 USP15 USP18 USP2 USP21 USP33 USP4 USP5 USP7 USP8 UTP14C VPS28 WDR34 WDYHV1 YOD1 ZBTB16 ZGPAT ZNF250 ZNF417 ZNF572 ZNF587
Entrez ID		23647	57159
HPRD ID		07209	05928
Ensembl ID		ENSG00000132254	ENSG00000138100
Uniprot IDs		B4DUZ3 B4DXH2 P53365	Q9BYV2
PDB IDs		1I49 1I4D 1I4L 1I4T 4DCN	3Q1D
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Signaling Cell Communication Signal Transduction Vesicle-mediated Transport Cell Projection Organization Response To Stimulus Regulation Of Signaling Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Organelle Organization Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signal Transduction Protein Localization Cellular Localization Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Growth Positive Regulation Of Cell Death Apoptotic Process Platelet Activation Protein Transport Programmed Cell Death Regulation Of Hydrogen Peroxide Metabolic Process Blood Coagulation Cell Death Death Cell Division Establishment Of Protein Localization Hemostasis Regulation Of Respiratory Burst Intracellular Transport Establishment Of Localization In Cell Regulation Of Cell Death Positive Regulation Of Lamellipodium Assembly Generation Of Neurons Golgi Vesicle Transport Protein Localization To Organelle Positive Regulation Of Lamellipodium Organization Neurogenesis Cell Projection Morphogenesis Membrane Invagination Cellular Copper Ion Homeostasis Negative Regulation Of JAK-STAT Cascade Cell Part Morphogenesis Positive Regulation Of Signal Transduction Developmental Process	Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Proteolysis Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Organelle Organization Regulation Of Protein Catabolic Process Protein Metabolic Process Histone Deubiquitination RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cellular Process Monoubiquitinated Protein Deubiquitination Histone Modification Gene Expression RNA Biosynthetic Process Chromatin Modification Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Chromatin Organization Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Chromosome Organization Cellular Response To Heat Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process
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