ARFIP2 and ARL1

Number of citations of the paper that reports this interaction (PMID 12972563)
32

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		ARFIP2	ARL1
Gene Name		ADP-ribosylation factor interacting protein 2	ADP-ribosylation factor-like 1
Image
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Plasma Membrane Cell Cortex Trans-Golgi Network Membrane	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Extracellular Vesicular Exosome
	Molecular Function	Protein Binding GTP Binding Protein Domain Specific Binding GTP-dependent Protein Binding Rac GTPase Binding Phosphatidylinositol-4-phosphate Binding	GTPase Activity GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Movement Of Cell Or Subcellular Component Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization	Golgi Organization Small GTPase Mediated Signal Transduction Toxin Metabolic Process Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARL1 CDKN2A CEP63 DTNBP1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 LY6D MAL2 RAC1 RAC2 SNX1 SOCS2 STAT3 TRIM54 USHBP1	7 interactors: ARFIP2 COPG2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC
Entrez ID		23647	400
HPRD ID		07209	04574
Ensembl ID		ENSG00000132254	ENSG00000120805
Uniprot IDs		B4DUZ3 B4DXH2 P53365	B4DZG7 P40616
PDB IDs		1I49 1I4D 1I4L 1I4T 4DCN	1UPT 4DCN
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Signaling Cell Communication Signal Transduction Vesicle-mediated Transport Cell Projection Organization Response To Stimulus Regulation Of Signaling Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Organelle Organization Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signal Transduction Protein Localization Cellular Localization Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Growth Positive Regulation Of Cell Death Apoptotic Process Platelet Activation Protein Transport Programmed Cell Death Regulation Of Hydrogen Peroxide Metabolic Process Blood Coagulation Cell Death Death Cell Division Establishment Of Protein Localization Hemostasis Regulation Of Respiratory Burst Intracellular Transport Establishment Of Localization In Cell Regulation Of Cell Death Positive Regulation Of Lamellipodium Assembly Generation Of Neurons Golgi Vesicle Transport Protein Localization To Organelle Positive Regulation Of Lamellipodium Organization Neurogenesis Cell Projection Morphogenesis Membrane Invagination Cellular Copper Ion Homeostasis Negative Regulation Of JAK-STAT Cascade Cell Part Morphogenesis Positive Regulation Of Signal Transduction Developmental Process	Intra-Golgi Vesicle-mediated Transport Protein Targeting To Golgi Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Protein Localization To Golgi Apparatus Golgi Vesicle Transport Establishment Of Protein Localization To Organelle Intracellular Protein Transport Protein Targeting Protein Localization To Organelle Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cytoplasmic Transport Protein Localization Establishment Of Localization In Cell Cellular Localization Recycling Endosome To Golgi Transport Late Endosome To Golgi Transport Regulation Of Protein Exit From Endoplasmic Reticulum Golgi Ribbon Formation Protein Targeting To Lysosome Protein Localization To Lysosome Positive Regulation Of Macroautophagy Transport Endomembrane System Organization Protein Targeting To Vacuole Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization To Vacuole Golgi To Plasma Membrane Transport Positive Regulation Of Autophagy Retrograde Vesicle-mediated Transport, Golgi To ER Ruffle Organization Positive Regulation Of Axon Extension Lysosomal Transport Lamellipodium Assembly Lamellipodium Organization Microtubule Anchoring Retrograde Transport, Endosome To Golgi
Tagcloud ?			actb arfgap2 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 mrfap1 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 rsl24d1 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2
Tagcloud (Difference) ?			actb arfgap2 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 mrfap1 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 rsl24d1 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2
Tagcloud (Intersection) ?