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CD2AP and NR2C2
Number of citations of the paper that reports this interaction (PMID
18654987
)
7
Data Source:
BioGRID
(two hybrid)
CD2AP
NR2C2
Gene Name
CD2-associated protein
nuclear receptor subfamily 2, group C, member 2
Image
Gene Ontology Annotations
Cellular Component
Ruffle
Nucleolus
Cytoplasm
Plasma Membrane
Cell-cell Junction
Actin Cytoskeleton
Filamentous Actin
Extracellular Vesicular Exosome
Nucleoplasm
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
SH3 Domain Binding
Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Transcription Coactivator Activity
Receptor Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
Biological Process
Protein Complex Assembly
Substrate-dependent Cell Migration, Cell Extension
Mitotic Nuclear Division
Signal Transduction
Negative Regulation Of Transforming Growth Factor Beta1 Production
Cell Division
Positive Regulation Of Protein Localization To Nucleus
Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Spermatogenesis
Nervous System Development
Gene Expression
Cerebellum Development
Cell Differentiation
Positive Regulation Of Embryonic Development
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Behavior
Meiotic Cell Cycle
Pathways
Nephrin interactions
Generic Transcription Pathway
Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Alzheimer's disease (late onset) (
21460841
)
Alcohol and nictotine co-dependence (
22488850
)
Protein-Protein Interactions
30 interactors:
BCAR1
CAPZA1
CBL
CD2
CTTN
FYN
GRB2
GZMB
HBP1
HCK
HOXC11
KHDRBS1
MVB12A
NPHS1
NPHS2
NR2C2
NR4A1
PDCD6IP
PIK3R1
PKD2
PSTPIP1
PTGES3
RAB4A
SH3GL2
SOS1
SOS2
SRC
UBC
WTIP
YES1
21 interactors:
AR
CD2AP
CDC37
CHUK
ESR1
FKBP5
HDAC4
HNF4A
HSP90AA1
HSP90AB1
IKBKB
ITSN2
JAZF1
KDM1A
NR2C1
NR2C2AP
PEBP1
RXRB
TAB1
TAB2
TRAF2
Entrez ID
23607
7182
HPRD ID
05026
03253
Ensembl ID
ENSG00000198087
Uniprot IDs
Q9Y5K6
F2YGU2
P49116
Q6PHZ7
PDB IDs
2FEI
2J6F
2J6K
2J6O
2J7I
3AA6
3LK4
3U23
3P0U
Enriched GO Terms of Interacting Partners
?
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Growth Factor Stimulus
Neurotrophin TRK Receptor Signaling Pathway
Response To Growth Factor
Neurotrophin Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Immune Response-regulating Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune System Process
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Signaling
Regulation Of Cellular Component Organization
Cell Communication
Signal Transduction
Leukocyte Migration
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Regulation Of ERBB Signaling Pathway
Locomotion
Cellular Response To Hormone Stimulus
Cellular Response To Organic Substance
Blood Coagulation
Hemostasis
Innate Immune Response
Cell Surface Receptor Signaling Pathway
Cell Migration
Cellular Response To Peptide Hormone Stimulus
Regulation Of Immune Response
Cellular Response To Peptide
Cell Motility
Response To Organic Substance
Immune Response
Regulation Of Immune System Process
Regulation Of Body Fluid Levels
Positive Regulation Of Organelle Organization
Regulation Of Cellular Process
Cellular Response To Stimulus
Wound Healing
Chemotaxis
T Cell Costimulation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Response To Stimulus
Intracellular Receptor Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Innate Immune Response
I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Initiation
Toll-like Receptor Signaling Pathway
Regulation Of Signal Transduction
Positive Regulation Of Metabolic Process
Hormone-mediated Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Activation Of Innate Immune Response
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Regulation Of Signaling
Toll-like Receptor 2 Signaling Pathway
Response To Organic Substance
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Cellular Response To Steroid Hormone Stimulus
Regulation Of Immune Response
Regulation Of Metabolic Process
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Innate Immune Response
Positive Regulation Of Immune System Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Immune System Process
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Immune Response
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Innate Immune Response
Immune Response-activating Cell Surface Receptor Signaling Pathway
Tagcloud
?
abca7
bin1
cass4
cd33
celf1
chapter
discoveries
drb1
drb5
epha1
fermt2
inpp5d
mef2c
ms4a4
ms4a6
nme8
picalm
pld3
psen1
psen2
ptk2b
rin3
slc24a4
sorl1
touch
trem2
trip4
unsuspected
zcwpw1
Tagcloud (Difference)
?
abca7
bin1
cass4
cd33
celf1
chapter
discoveries
drb1
drb5
epha1
fermt2
inpp5d
mef2c
ms4a4
ms4a6
nme8
picalm
pld3
psen1
psen2
ptk2b
rin3
slc24a4
sorl1
touch
trem2
trip4
unsuspected
zcwpw1
Tagcloud (Intersection)
?