WBP1 and WWP1

Number of citations of the paper that reports this interaction (PMID 9169421)
29

Data Source:
HPRD (in vitro, in vivo)

		WBP1	WWP1
Gene Name		WW domain binding protein 1	WW domain containing E3 ubiquitin protein ligase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding WW Domain Binding	Ubiquitin-protein Transferase Activity Protein Binding Ligase Activity
	Biological Process	Biological_process	Signal Transduction Central Nervous System Development Protein Ubiquitination Ion Transmembrane Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell Transmembrane Transport
Pathways			Downregulation of ERBB4 signaling Ion channel transport Antigen processing: Ubiquitination & Proteasome degradation Stimuli-sensing channels Class I MHC mediated antigen processing & presentation Signaling by ERBB4 Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CACNA1A MAGI1 NEDD4 WWP1 WWP2 YAP1	47 interactors: ARRDC1 ARRDC2 ARRDC3 ASH2L ATN1 CLCN5 CPSF6 DAG1 DAZAP2 DIDO1 EWSR1 FAM189A2 FBXL18 H2AFY2 IKBKG IL2RG IL6R KLF2 KLF5 LAPTM5 LATS1 LNX1 LZTR1 NFE2 NOTCH1 PCBD1 PHF20L1 PRKAA2 PTEN RASA1 RNF11 RTN4 SCNN1A SFTPC SMAD3 SMAD5 STAT6 TFAP2A TGIF1 TP53BP2 TRAF4 UBC UBE2L3 WBP1 WBP2 YWHAQ ZNF638
Entrez ID		23559	11059
HPRD ID		09510	03811
Ensembl ID		ENSG00000239779	ENSG00000123124
Uniprot IDs		A8MX15 Q96G27	Q9H0M0
PDB IDs			1ND7 2OP7
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Interaction With Host Negative Regulation Of Biosynthetic Process Regulation Of Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Protein K63-linked Ubiquitination Regulation Of Membrane Potential Regulation Of Potassium Ion Transmembrane Transport Viral Entry Into Host Cell Entry Into Host Cell Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Potassium Ion Transport Regulation Of Ion Transmembrane Transport Regulation Of Sodium Ion Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Cerebellar Molecular Layer Development Transmission Of Virus Development Involved In Symbiotic Interaction Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Vestibular Nucleus Development Cellular Response To Radiation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Protein Polyubiquitination Synapse Organization Cellular Macromolecule Catabolic Process Regulation Of Cell Development Viral Life Cycle Gamma-aminobutyric Acid Secretion Regulation Of Metabolic Process Mesenchyme Development Regulation Of Acetylcholine Secretion, Neurotransmission Heart Morphogenesis Rhythmic Synaptic Transmission Progesterone Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Proteasomal Protein Catabolic Process Negative Regulation Of Signal Transduction	Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Response To Organic Substance RNA Metabolic Process Organ Development Regulation Of RNA Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Metabolic Process Apoptotic Process Gene Expression Regulation Of Transcription, DNA-templated Programmed Cell Death Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Death Death Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter System Development Cellular Macromolecule Biosynthetic Process Positive Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Ossification Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Response To Organic Cyclic Compound Positive Regulation Of Cellular Protein Metabolic Process Tube Development Positive Regulation Of Protein Modification Process Multicellular Organismal Development Negative Regulation Of Signaling Tissue Development Cellular Response To Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Response To Growth Factor Nucleobase-containing Compound Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Signal Transduction Developmental Process Positive Regulation Of Ligase Activity Epithelium Development
Tagcloud ?		ancestor antagonizing bilaterian branchiostoma ckamp44 cysteines cyyr1 distantly duf2650 est expansions fam159 floridae founding invertebrates kiaa1644 kowalevskii metazoa occurrences porifera proteomes refer saccoglossus shisa shisa9 stmc6 subfamilies tmem92 vopp1	biol chem consisting contains e2 ermekova gavva globin gst hematopoietic heterodimer homologue interacted j ligase motifs multimeric p18 p45 phage ppxy sh3 shen spanning sudol tandem transactivation ubiquitous
Tagcloud (Difference) ?		ancestor antagonizing bilaterian branchiostoma ckamp44 cysteines cyyr1 distantly duf2650 est expansions fam159 floridae founding invertebrates kiaa1644 kowalevskii metazoa occurrences porifera proteomes refer saccoglossus shisa shisa9 stmc6 subfamilies tmem92 vopp1	biol chem consisting contains e2 ermekova gavva globin gst hematopoietic heterodimer homologue interacted j ligase motifs multimeric p18 p45 phage ppxy sh3 shen spanning sudol tandem transactivation ubiquitous
Tagcloud (Intersection) ?