WBP1 and MAGI1

Number of citations of the paper that reports this interaction (PubMedID 9169421)
0

Data Source:
BioGRID (unspecified method)

		WBP1	MAGI1
Description		WW domain binding protein 1	membrane associated guanylate kinase, WW and PDZ domain containing 1
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GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Membrane Cell Junction Cell Projection Anchoring Junction Cell Periphery
	Molecular Function	Protein Binding WW Domain Binding	Nucleotide Binding Protein Binding ATP Binding Alpha-actinin Binding
	Biological Process		Endothelial Cell Morphogenesis Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Protein-containing Complex Assembly
Pathways
Drugs
Diseases
GWAS			Adolescent idiopathic scoliosis ( 28334814) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cirrhosis (alcohol related) ( 32853455) Cobalt levels ( 26025379) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Cortical surface area (MOSTest) ( 32665545) Crohn's disease-related phenotypes ( 25557950) Declining hemoglobin trajectory in blood donors ( 33491795) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Knee osteoarthritis ( 28916551) Neurociticism ( 29500382) Neuroticism ( 25993607) Nicotine dependence symptom count ( 25555482) Ocular sarcoidosis ( 32141793) Ocular sarcoidosis in sarcoidosis ( 32141793) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 23534349) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tinnitus ( 33742053)
Interacting Genes		10 interacting genes: CACNA1A COPA EPN2 MAGI1 NEDD4 SMCO4 WWP1 WWP2 YAP1 ZMYND10	27 interacting genes: ACTN4 ADGRB1 AMOT ASIC3 ATF6 ATN1 CLCN5 CRHR1 CTNNB1 DAG1 GBP2 IGSF5 IL6R LPP LRP2 NET1 RAC1 RASA1 RASL11B RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2
Entrez ID		23559	9223
HPRD ID		09510	04020
Ensembl ID		ENSG00000239779	ENSG00000151276
Uniprot IDs		A0A384P602 Q96G27	Q96QZ7
PDB IDs		1JMQ 1K5R	1WBP 2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU 5N7D 5N7F 5N7G 6TWU 6TWX 6TWY 7P71
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Potassium Ion Export Across Plasma Membrane Potassium Channel Inhibitor Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Notch Signaling Pathway Ubiquitin Ligase Complex Proline-rich Region Binding Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transport Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Notch Signaling Pathway Ubiquitin-protein Transferase Activity Mesenchyme Development Formation Of Structure Involved In A Symbiotic Process Enterocyte Differentiation Positive Regulation Of Motile Cilium Assembly Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Cation Transmembrane Transport Protein K63-linked Ubiquitination Negative Regulation Of Monoatomic Ion Transmembrane Transport Ubiquitin Protein Ligase Activity Regulation Of Potassium Ion Transport Channel Inhibitor Activity Anchoring Junction Regulation Of Cilium Assembly Negative Regulation Of Monoatomic Ion Transport Membrane Phosphothreonine Residue Binding TEAD-YAP Complex Cytoplasm Protein Localization To Cell Leading Edge Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transmembrane Transport Bicellular Tight Junction Lateral Mesoderm Development Cardiac Muscle Tissue Regeneration Symbiont Entry Into Host Cell Pancreatic Juice Secretion Transmembrane Transporter Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Phosphoserine Residue Binding Beta-2 Adrenergic Receptor Binding Ubiquitin-dependent Protein Catabolic Process Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Modification-dependent Protein Catabolic Process Biological Process Involved In Interaction With Host	Anchoring Junction Ribosomal Protein S6 Kinase Activity Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Stress Fiber Trans-synaptic Signaling Synaptic Signaling Positive Regulation Of Developmental Process Engulfment Of Apoptotic Cell Focal Adhesion Bicellular Tight Junction Regulation Of Cell Communication Regulation Of Signaling Synapse Regulation Of Synapse Organization Tube Morphogenesis Regulation Of Intracellular Signal Transduction Chemical Synaptic Transmission Positive Regulation Of Actin Filament Bundle Assembly TORC1 Signaling Signal Transduction Regulation Of Cellular Component Organization Midbrain Dopaminergic Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Vasculogenesis Animal Organ Development Glutamatergic Synapse Lamellipodium Forebrain Development Cell Junction Regulation Of Signal Transduction Cell-cell Signaling TOR Signaling Gastrulation With Mouth Forming Second Regulation Of Cell-substrate Adhesion Apical Part Of Cell Enzyme Binding Cranial Skeletal System Development Anatomical Structure Arrangement Signaling Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Stress Fiber Assembly Cell Communication Epithelial Tube Branching Involved In Lung Morphogenesis Regulation Of Gliogenesis Blood Vessel Morphogenesis Regulation Of Translation In Response To Stress Cell-matrix Adhesion
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