WWP1 and FBXL18

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		WWP1	FBXL18
Gene Name		WW domain containing E3 ubiquitin protein ligase 1	F-box and leucine-rich repeat protein 18
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ligase Activity
	Biological Process	Signal Transduction Central Nervous System Development Protein Ubiquitination Ion Transmembrane Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell Transmembrane Transport
Pathways		Downregulation of ERBB4 signaling Ion channel transport Antigen processing: Ubiquitination & Proteasome degradation Stimuli-sensing channels Class I MHC mediated antigen processing & presentation Signaling by ERBB4 Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: ARRDC1 ARRDC2 ARRDC3 ASH2L ATN1 CLCN5 CPSF6 DAG1 DAZAP2 DIDO1 EWSR1 FAM189A2 FBXL18 H2AFY2 IKBKG IL2RG IL6R KLF2 KLF5 LAPTM5 LATS1 LNX1 LZTR1 NFE2 NOTCH1 PCBD1 PHF20L1 PRKAA2 PTEN RASA1 RNF11 RTN4 SCNN1A SFTPC SMAD3 SMAD5 STAT6 TFAP2A TGIF1 TP53BP2 TRAF4 UBC UBE2L3 WBP1 WBP2 YWHAQ ZNF638	21 interactors: CALCOCO2 FHL3 GOLGA2 HNRNPK KRT40 KRTAP10-3 KRTAP4-12 MDFI MID2 MTUS2 NOTCH2NL PLSCR1 PNMA1 PSMA3 PSTPIP1 RBPMS TFCP2 TRAF1 TRAF4 WWP1 WWP2
Entrez ID		11059	80028
HPRD ID		03811	07753
Ensembl ID		ENSG00000123124	ENSG00000155034
Uniprot IDs		Q9H0M0	F5H4Z4 Q96ME1
PDB IDs		1ND7 2OP7
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Response To Organic Substance RNA Metabolic Process Organ Development Regulation Of RNA Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Metabolic Process Apoptotic Process Gene Expression Regulation Of Transcription, DNA-templated Programmed Cell Death Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Death Death Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter System Development Cellular Macromolecule Biosynthetic Process Positive Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Ossification Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Response To Organic Cyclic Compound Positive Regulation Of Cellular Protein Metabolic Process Tube Development Positive Regulation Of Protein Modification Process Multicellular Organismal Development Negative Regulation Of Signaling Tissue Development Cellular Response To Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Response To Growth Factor Nucleobase-containing Compound Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Signal Transduction Developmental Process Positive Regulation Of Ligase Activity Epithelium Development	Viral Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Nitrogen Compound Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Binding Proteasomal Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Protein Metabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Viral Process Positive Regulation Of Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Defense Response Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Negative Regulation Of Binding Response To Stimulus Interaction With Host Immune System Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of JNK Cascade Positive Regulation Of Protein Modification Process Inflammatory Response Regulation Of Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Apoptotic Process Phosphatidylserine Biosynthetic Process Regulation Of Metabolic Process Programmed Cell Death Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Binding Modification-dependent Protein Catabolic Process Regulation Of Viral Process Cell Death Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Protein Localization To Microtubule Death Regulation Of JNK Cascade Regulation Of Cellular Process Proteolysis Involved In Cellular Protein Catabolic Process
Tagcloud ?		biol chem consisting contains e2 ermekova gavva globin gst hematopoietic heterodimer homologue interacted j ligase motifs multimeric p18 p45 phage ppxy sh3 shen spanning sudol tandem transactivation ubiquitous
Tagcloud (Difference) ?		biol chem consisting contains e2 ermekova gavva globin gst hematopoietic heterodimer homologue interacted j ligase motifs multimeric p18 p45 phage ppxy sh3 shen spanning sudol tandem transactivation ubiquitous
Tagcloud (Intersection) ?