WWP1 and PHF20L1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		WWP1	PHF20L1
Gene Name		WW domain containing E3 ubiquitin protein ligase 1	PHD finger protein 20-like 1
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Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ligase Activity	Protein Binding Zinc Ion Binding
	Biological Process	Signal Transduction Central Nervous System Development Protein Ubiquitination Ion Transmembrane Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell Transmembrane Transport
Pathways		Downregulation of ERBB4 signaling Ion channel transport Antigen processing: Ubiquitination & Proteasome degradation Stimuli-sensing channels Class I MHC mediated antigen processing & presentation Signaling by ERBB4 Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: ARRDC1 ARRDC2 ARRDC3 ASH2L ATN1 CLCN5 CPSF6 DAG1 DAZAP2 DIDO1 EWSR1 FAM189A2 FBXL18 H2AFY2 IKBKG IL2RG IL6R KLF2 KLF5 LAPTM5 LATS1 LNX1 LZTR1 NFE2 NOTCH1 PCBD1 PHF20L1 PRKAA2 PTEN RASA1 RNF11 RTN4 SCNN1A SFTPC SMAD3 SMAD5 STAT6 TFAP2A TGIF1 TP53BP2 TRAF4 UBC UBE2L3 WBP1 WBP2 YWHAQ ZNF638	9 interactors: APP CASP10 ELAVL4 KDM1A LYAR TERT UBC WWP1 ZNF471
Entrez ID		11059	51105
HPRD ID		03811	15125
Ensembl ID		ENSG00000123124	ENSG00000129292
Uniprot IDs		Q9H0M0	A8MW92 F8W9L8 Q9H8G4
PDB IDs		1ND7 2OP7	2EQM 2EQU 2JTF
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Response To Organic Substance RNA Metabolic Process Organ Development Regulation Of RNA Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Metabolic Process Apoptotic Process Gene Expression Regulation Of Transcription, DNA-templated Programmed Cell Death Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Death Death Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter System Development Cellular Macromolecule Biosynthetic Process Positive Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Ossification Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Response To Organic Cyclic Compound Positive Regulation Of Cellular Protein Metabolic Process Tube Development Positive Regulation Of Protein Modification Process Multicellular Organismal Development Negative Regulation Of Signaling Tissue Development Cellular Response To Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Response To Growth Factor Nucleobase-containing Compound Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Signal Transduction Developmental Process Positive Regulation Of Ligase Activity Epithelium Development	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway RNA Metabolic Process Gene Expression Negative Regulation Of Cellular Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Production Of SiRNA Involved In RNA Interference Negative Regulation Of Gene Expression Negative Regulation Of RNA Interference Synaptic Growth At Neuromuscular Junction Transcription, RNA-templated RNA Processing Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Regulation Of Signal Transduction Notch Signaling Pathway Telomere Formation Via Telomerase Collateral Sprouting In Absence Of Injury Age-dependent Telomere Shortening Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Cell Death Regulation Of Protein Binding Positive Regulation Of Wnt Signaling Pathway Heterocycle Metabolic Process Telomere Maintenance Via Telomere Shortening Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Signaling Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Collateral Sprouting Axon Midline Choice Point Recognition Cellular Nitrogen Compound Metabolic Process Viral Life Cycle Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Intracellular Receptor Signaling Pathway Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Telomere Assembly Axon Choice Point Recognition Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Histone H3-K9 Demethylation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K4 Demethylation Negative Regulation Of Protein Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Tagcloud ?		biol chem consisting contains e2 ermekova gavva globin gst hematopoietic heterodimer homologue interacted j ligase motifs multimeric p18 p45 phage ppxy sh3 shen spanning sudol tandem transactivation ubiquitous	10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		biol chem consisting contains e2 ermekova gavva globin gst hematopoietic heterodimer homologue interacted j ligase motifs multimeric p18 p45 phage ppxy sh3 shen spanning sudol tandem transactivation ubiquitous	10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?