SGK1 and MAGEA1

Number of citations of the paper that reports this interaction (PMID 20368287)
12

Data Source:
BioGRID (two hybrid)

		SGK1	MAGEA1
Gene Name		serum/glucocorticoid regulated kinase 1	melanoma antigen family A, 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Plasma Membrane	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Calcium Channel Regulator Activity Protein Binding ATP Binding Potassium Channel Regulator Activity Sodium Channel Regulator Activity Chloride Channel Regulator Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	Regulation Of Cell Growth Protein Phosphorylation Sodium Ion Transport Apoptotic Process Response To Stress Cellular Response To DNA Damage Stimulus Long-term Memory Regulation Of Blood Pressure Regulation Of Cell Migration Positive Regulation Of Transporter Activity Ion Transmembrane Transport Regulation Of Cell Proliferation Regulation Of Apoptotic Process Regulation Of Catalytic Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Transmembrane Transport Regulation Of Gastric Acid Secretion Renal Sodium Ion Absorption	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Notch Signaling Pathway
Pathways		Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS		Body mass index (interaction) ( 23192594) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		31 interactors: BRAF CAMKK1 CARHSP1 CDKN1B CREB1 FANCA FOXO3 GADD45G GSK3A GSK3B IKBKG KCNJ1 KPNA2 MAGEA1 MAPK7 MAPT MLLT3 NDRG1 NEDD4 NEDD4L NEK6 PDK1 PDK2 PDPK1 PIK3CA PPP2CA RABAC1 RICTOR SLC1A3 SLC9A3R2 TMEM184C	18 interactors: C19orf66 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK MIEF1 PBX3 RAB17 SELPLG SFN SGK1 SH3GLB2 SNW1 TRIM31 UQCRB ZNF564
Entrez ID		6446	4100
HPRD ID		04264	02059
Ensembl ID		ENSG00000118515	ENSG00000198681
Uniprot IDs		E9PR89 O00141	P43355
PDB IDs		2R5T 3HDM 3HDN	1W72 3BO8
Enriched GO Terms of Interacting Partners?		Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Phosphatidylinositol-mediated Signaling Response To Growth Factor Fc-epsilon Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Signaling Negative Regulation Of Signal Transduction Signaling Regulation Of Protein Metabolic Process Response To Stress Apoptotic Process Cell Communication Programmed Cell Death Innate Immune Response Cell Death Death Regulation Of Signal Transduction Regulation Of Immune Response Response To Inorganic Substance Response To Metal Ion Response To Organic Substance Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Phosphorylation Cellular Response To Stress Regulation Of Protein Kinase Activity Cell Surface Receptor Signaling Pathway Immune Response Protein Phosphorylation Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Regulation Of Intracellular Signal Transduction Response To Peptide Hormone Immune System Process	Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Mitochondrion Organization Regulation Of Viral Transcription Positive Regulation Of Mitochondrial Fission Interferon-gamma-mediated Signaling Pathway Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Fission Antigen Processing And Presentation Of Endogenous Antigen Cellular Response To Interferon-gamma Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Response To Interferon-gamma Negative Regulation Of Viral Transcription Detection Of Bacterium Positive Regulation Of Organelle Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Viral Process Mitochondrial Fission Detection Of Biotic Stimulus Release Of Cytochrome C From Mitochondria Interaction With Symbiont Viral Process Negative Regulation Of Innate Immune Response Positive Regulation Of T Cell Mediated Cytotoxicity Cellular Response To Cytokine Stimulus Regulation Of T Cell Mediated Cytotoxicity Response To Stress Cellular Response To Organic Substance Positive Regulation Of Leukocyte Mediated Cytotoxicity Response To Cytokine Mitochondrial Membrane Fission Posterior Compartment Specification Anterior Compartment Pattern Formation Dynamin Polymerization Involved In Mitochondrial Fission Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Cell Killing Regulation Of Cellular Component Organization Regulation Of Leukocyte Mediated Cytotoxicity Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Positive Regulation Of Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Response To Type I Interferon Apoptotic Mitochondrial Changes Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Negative Regulation Of Viral Process Positive Regulation Of Protein Transport
Tagcloud ?		apical autophosphorylate autophosphorylation c4 cer ceramide cf cftr chloride coincidently conductance corrects cystic defect deltaf508 explants folding hypersecretion inactivates mutual pdk1 permit phosphorylates physiologically ser suppresses thr traffic trafficking	acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis
Tagcloud (Difference) ?		apical autophosphorylate autophosphorylation c4 cer ceramide cf cftr chloride coincidently conductance corrects cystic defect deltaf508 explants folding hypersecretion inactivates mutual pdk1 permit phosphorylates physiologically ser suppresses thr traffic trafficking	acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis
Tagcloud (Intersection) ?