SGK1 and CARHSP1

Number of citations of the paper that reports this interaction (PMID 15910284)
8

Data Source:
BioGRID (pull down)

		SGK1	CARHSP1
Gene Name		serum/glucocorticoid regulated kinase 1	calcium regulated heat stable protein 1, 24kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Plasma Membrane	Cytoplasmic Exosome (RNase Complex) Cytoplasmic MRNA Processing Body Cytosol P Granule Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Calcium Channel Regulator Activity Protein Binding ATP Binding Potassium Channel Regulator Activity Sodium Channel Regulator Activity Chloride Channel Regulator Activity	DNA Binding MRNA 3'-UTR Binding Phosphatase Binding
	Biological Process	Regulation Of Cell Growth Protein Phosphorylation Sodium Ion Transport Apoptotic Process Response To Stress Cellular Response To DNA Damage Stimulus Long-term Memory Regulation Of Blood Pressure Regulation Of Cell Migration Positive Regulation Of Transporter Activity Ion Transmembrane Transport Regulation Of Cell Proliferation Regulation Of Apoptotic Process Regulation Of Catalytic Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Transmembrane Transport Regulation Of Gastric Acid Secretion Renal Sodium Ion Absorption	Regulation Of Transcription, DNA-templated Intracellular Signal Transduction Regulation Of MRNA Stability
Pathways		Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS		Body mass index (interaction) ( 23192594) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		31 interactors: BRAF CAMKK1 CARHSP1 CDKN1B CREB1 FANCA FOXO3 GADD45G GSK3A GSK3B IKBKG KCNJ1 KPNA2 MAGEA1 MAPK7 MAPT MLLT3 NDRG1 NEDD4 NEDD4L NEK6 PDK1 PDK2 PDPK1 PIK3CA PPP2CA RABAC1 RICTOR SLC1A3 SLC9A3R2 TMEM184C	17 interactors: AKT1 DOCK8 KRTAP10-3 KRTAP10-7 KRTAP10-8 NOTCH2NL PIAS3 PIN1 PNMA1 RPS6KA1 SGK1 SMN1 STC2 STYX TK1 TRAF1 TSC22D1
Entrez ID		6446	23589
HPRD ID		04264	08515
Ensembl ID		ENSG00000118515	ENSG00000153048
Uniprot IDs		E9PR89 O00141	Q9Y2V2
PDB IDs		2R5T 3HDM 3HDN	3AQQ
Enriched GO Terms of Interacting Partners?		Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Phosphatidylinositol-mediated Signaling Response To Growth Factor Fc-epsilon Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Signaling Negative Regulation Of Signal Transduction Signaling Regulation Of Protein Metabolic Process Response To Stress Apoptotic Process Cell Communication Programmed Cell Death Innate Immune Response Cell Death Death Regulation Of Signal Transduction Regulation Of Immune Response Response To Inorganic Substance Response To Metal Ion Response To Organic Substance Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Phosphorylation Cellular Response To Stress Regulation Of Protein Kinase Activity Cell Surface Receptor Signaling Pathway Immune Response Protein Phosphorylation Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Regulation Of Intracellular Signal Transduction Response To Peptide Hormone Immune System Process	Regulation Of Apoptotic Process Regulation Of Cell Death Maternal Placenta Development Regulation Of Growth Glycogen Cell Differentiation Involved In Embryonic Placenta Development Fetal Process Involved In Parturition Memory T Cell Proliferation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Stimulus Regulation Of Cell Growth Multicellular Organismal Reproductive Process Maternal Process Involved In Female Pregnancy Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Multicellular Organism Reproduction Negative Regulation Of Cysteine-type Endopeptidase Activity Skeletal Muscle Cell Proliferation Positive Regulation Of Hepatic Stellate Cell Activation MAPK Export From Nucleus Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Response To Stress Response To Hormone Response To Nutrient Levels Cellular Response To Oxygen Levels Response To Organic Substance Apoptotic Process Negative Regulation Of Cell Death Positive Regulation Of Cell Growth Programmed Cell Death Response To Extracellular Stimulus Renal Sodium Ion Absorption Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Regulation Of Metabolic Process Reproduction Cell Death Death Renal Sodium Ion Transport Response To UV-A Response To Cortisol Thymidine Metabolic Process Negative Regulation Of MAPK Cascade Activation-induced Cell Death Of T Cells Regulation Of Gastric Acid Secretion Single Organism Reproductive Process Positive Regulation Of Apoptotic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle
Tagcloud ?		apical autophosphorylate autophosphorylation c4 cer ceramide cf cftr chloride coincidently conductance corrects cystic defect deltaf508 explants folding hypersecretion inactivates mutual pdk1 permit phosphorylates physiologically ser suppresses thr traffic trafficking
Tagcloud (Difference) ?		apical autophosphorylate autophosphorylation c4 cer ceramide cf cftr chloride coincidently conductance corrects cystic defect deltaf508 explants folding hypersecretion inactivates mutual pdk1 permit phosphorylates physiologically ser suppresses thr traffic trafficking
Tagcloud (Intersection) ?