CNOT9

Description		CCR4-NOT transcription complex subunit 9
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GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Membrane CCR4-NOT Complex CCR4-NOT Core Complex Protein-containing Complex
	Molecular Function	Transcription Coactivator Activity Epidermal Growth Factor Receptor Binding Protein Binding Kinase Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Catabolic Process Regulation Of Translation Sex Differentiation Negative Regulation Of Translation Cytokine-mediated Signaling Pathway Regulatory NcRNA-mediated Gene Silencing Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of DNA-templated Transcription
Pathways		Deadenylation of mRNA Activation of anterior HOX genes in hindbrain development during early embryogenesis TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain M-decay: degradation of maternal mRNAs by maternally stored factors
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: AKT1 EGFR GADD45A GADD45B GADD45G GIGYF1 GIGYF2 GRB10 MESD MYB OBI1
Entrez ID		9125
HPRD ID		08828
Ensembl ID		ENSG00000144580
Uniprot IDs		D5MQE1 Q92600
PDB IDs		2FV2 4CRU 4CRV 4CT6 4CT7 5LSW 5ONA 5ONB 6HOM 6HON 9FL8
Enriched GO Terms of Interacting Partners?		Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of P38MAPK Cascade Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of P38MAPK Cascade Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Protein Localization To Membrane Positive Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell Cycle Enzyme-linked Receptor Protein Signaling Pathway Response To UV-A Kinase Binding Positive Regulation Of JNK Cascade Protein-containing Complex Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Signal Transduction Regulation Of Phosphorylation Regulation Of Apoptotic Process Regulation Of JNK Cascade Regulation Of G1/S Transition Of Mitotic Cell Cycle Embryonic Organ Development Regulation Of Programmed Cell Death Regulation Of Glycogen Biosynthetic Process Regulation Of Protein Localization To Membrane Positive Regulation Of MAPK Cascade Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Apoptotic Process Regulation Of Glycogen Metabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Phosphorus Metabolic Process Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Translational Initiation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Response To Epidermal Growth Factor Regulation Of MAPK Cascade Positive Regulation Of Fibroblast Proliferation Positive Regulation Of MiRNA Transcription Regulation Of TRNA Methylation Regulation Of D-glucose Import Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Multivesicular Body, Internal Vesicle Lumen Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Cycle G1/S Phase Transition Epidermal Growth Factor Receptor Signaling Pathway
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