MAST2 and DYNLL1

Number of citations of the paper that reports this interaction (PMID 14760703)
24

Data Source:
HPRD (in vitro)

		MAST2	DYNLL1
Gene Name		microtubule associated serine/threonine kinase 2	dynein, light chain, LC8-type 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Microtubule Cytoskeleton	Kinetochore Nucleus Cytoplasm Mitochondrion Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane COP9 Signalosome Membrane Extracellular Vesicular Exosome Primary Cilium Mitotic Spindle Ciliary Tip
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Phosphatase Binding	Motor Activity Protein Binding Protein C-terminus Binding Enzyme Binding Protein Domain Specific Binding Nitric-oxide Synthase Regulator Activity Protein Homodimerization Activity
	Biological Process	Protein Phosphorylation Regulation Of Interleukin-12 Biosynthetic Process Spermatid Differentiation	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transport Apoptotic Process Organelle Organization Microtubule-based Process Female Gamete Generation Anatomical Structure Morphogenesis Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Substantia Nigra Development Actin Cytoskeleton Organization Negative Regulation Of Phosphorylation Regulation Of Catalytic Activity Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Organelle biogenesis and maintenance Activation of BH3-only proteins Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic Intraflagellar transport Loss of proteins required for interphase microtubule organizationÂ from the centrosome Activation of BIM and translocation to mitochondria Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Programmed Cell Death Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes Adaptive Immune System Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP CDHR2 DYNLL1 PTEN RPS27A SH3GL2 SLC34A1 SLC9A3 SMN1 SNTB2 STK36 SUMO2 TK1 TRAF2 TRAF6	77 interactors: ACTB ACTC1 ACTG1 ALDOA AMBRA1 AMOTL2 B3GALT4 BCAS1 BCL2L11 BMF C14orf1 CA2 CACNB1 CCDC36 CLIP2 CS DAZ1 DLG4 DLGAP1 DNAJB9 DNM2 DNM3 DNMT1 DYNC1H1 DYNC1I1 EEF1A1 GAPDH GLUD1 GLUL GNB2L1 GPHN GRIN3A HIP1R HSPA8 INPP1 IQUB KANK2 LDHA MAP1B MARK3 MAST2 ME2 MTA1 MTR MYO10 MYO5A NDUFA4L2 NFKBIA NOS1 NRF1 NTRK1 NTRK2 NTRK3 PAK1 PAN2 PARD3 PAX6 PFKM PFKP PKIA PKIB PKIG POLH RAB4A RGS2 SHROOM3 TERT THAP8 TNFRSF14 TP53BP1 TUBA3C TUBB TXNDC17 VIM ZHX1 ZMYND11 ZNF354A
Entrez ID		23139	8655
HPRD ID		11294	03334
Ensembl ID		ENSG00000086015	ENSG00000088986
Uniprot IDs		Q6P0Q8	P63167 Q6FGH9
PDB IDs		2KQF 2KYL	1CMI 3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Proteolysis Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Component Assembly I-kappaB Kinase/NF-kappaB Signaling Neurotrophin TRK Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Neurotrophin Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Antigen Processing And Presentation Of Peptide Antigen Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Programmed Cell Death Toll-like Receptor 4 Signaling Pathway Regulation Of ERBB Signaling Pathway Positive Regulation Of Apoptotic Process Cell Death Positive Regulation Of Programmed Cell Death Death Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Cell Death Antigen Processing And Presentation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Immunoglobulin Secretion Regulation Of Proteolysis Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Signal Transduction Positive Regulation Of T Cell Cytokine Production Regulation Of Phosphorylation Pattern Recognition Receptor Signaling Pathway Regulation Of Kinase Activity Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Antigen Receptor-mediated Signaling Pathway Innate Immune Response Activation Of Innate Immune Response Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Immune System Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of T Cell Cytokine Production	Nervous System Development Movement Of Cell Or Subcellular Component Cell Differentiation Developmental Process Regulation Of Cellular Component Organization Response To Organic Substance Regulation Of Cellular Localization Neuron Projection Morphogenesis Axonogenesis Cellular Response To Stimulus Synapse Organization Neuron Projection Development Neuron Development Regulation Of Cellular Protein Metabolic Process Response To Stimulus Neuron Differentiation Regulation Of Protein Metabolic Process Axon Development Cell Projection Morphogenesis Response To External Stimulus Anatomical Structure Morphogenesis Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Cell Part Morphogenesis Cellular Process Negative Regulation Of CAMP-dependent Protein Kinase Activity Positive Regulation Of Protein Homooligomerization Cell Morphogenesis Axon Guidance Negative Regulation Of Phosphorylation Regulation Of Cellular Process Glycolytic Process Locomotion Cell Development Negative Regulation Of Protein Phosphorylation Cytoskeleton Organization Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Membrane Organization Regulation Of CAMP-dependent Protein Kinase Activity Cell Morphogenesis Involved In Differentiation Anatomical Structure Development Generation Of Neurons System Development Response To Stress Regulation Of Protein Phosphorylation Multicellular Organismal Development Neuromuscular Junction Development Pyruvate Metabolic Process Actin Filament-based Process
Tagcloud ?			1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating
Tagcloud (Difference) ?			1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating
Tagcloud (Intersection) ?