MAST2 and SLC34A1

Number of citations of the paper that reports this interaction (PMID 11099500)
37

Data Source:
HPRD (two hybrid)

		MAST2	SLC34A1
Gene Name		microtubule associated serine/threonine kinase 2	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Microtubule Cytoskeleton	Endosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Brush Border Membrane Membrane-bounded Vesicle Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Phosphatase Binding	Protein Binding Symporter Activity Sodium-dependent Phosphate Transmembrane Transporter Activity PDZ Domain Binding Protein Complex Binding Protein Homodimerization Activity
	Biological Process	Protein Phosphorylation Regulation Of Interleukin-12 Biosynthetic Process Spermatid Differentiation	Ossification Kidney Development Ion Transport Sodium Ion Transport Phosphate Ion Transport Glycoprotein Metabolic Process Response To Lead Ion Response To Magnesium Ion Response To Estradiol Response To Vitamin A Response To Potassium Ion Indole Metabolic Process Response To Drug Sodium-dependent Phosphate Transport Positive Regulation Of Membrane Potential Response To Cadmium Ion Response To Mercury Ion Bone Remodeling Protein Homooligomerization Phosphate Ion Homeostasis Transmembrane Transport Response To Growth Hormone Cellular Response To Metal Ion Cellular Response To Parathyroid Hormone Stimulus Tricarboxylic Acid Metabolic Process Cellular Response To Staurosporine Response To Thyroid Hormone Dentinogenesis Gentamycin Metabolic Process Arsenate Ion Transmembrane Transport Positive Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Phosphate Transmembrane Transport
Pathways			Sodium-coupled phosphate cotransporters Type II Na+/Pi cotransporters Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport
Drugs
Diseases
GWAS			Activated partial thromboplastin time ( 22703881) Chronic kidney disease ( 20383146) Nephrolithiasis ( 22396660)
Protein-Protein Interactions		15 interactors: APP CDHR2 DYNLL1 PTEN RPS27A SH3GL2 SLC34A1 SLC9A3 SMN1 SNTB2 STK36 SUMO2 TK1 TRAF2 TRAF6	10 interactors: BSPRY FHL2 HPCAL1 HSP90AA1 HSP90AB1 MAST2 PEX19 SLC9A3R1 SLC9A3R2 YIF1A
Entrez ID		23139	6569
HPRD ID		11294	08918
Ensembl ID		ENSG00000086015	ENSG00000131183
Uniprot IDs		Q6P0Q8	Q06495 Q7Z725 Q86VN6
PDB IDs		2KQF 2KYL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Proteolysis Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Component Assembly I-kappaB Kinase/NF-kappaB Signaling Neurotrophin TRK Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Neurotrophin Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Antigen Processing And Presentation Of Peptide Antigen Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Programmed Cell Death Toll-like Receptor 4 Signaling Pathway Regulation Of ERBB Signaling Pathway Positive Regulation Of Apoptotic Process Cell Death Positive Regulation Of Programmed Cell Death Death Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Cell Death Antigen Processing And Presentation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Immunoglobulin Secretion Regulation Of Proteolysis Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Signal Transduction Positive Regulation Of T Cell Cytokine Production Regulation Of Phosphorylation Pattern Recognition Receptor Signaling Pathway Regulation Of Kinase Activity Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Antigen Receptor-mediated Signaling Pathway Innate Immune Response Activation Of Innate Immune Response Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Immune System Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of T Cell Cytokine Production	Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Protein Folding Intracellular Protein Transmembrane Transport Regulation Of Nitric Oxide Biosynthetic Process Protein Transmembrane Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Heat Renal Phosphate Ion Absorption Negative Regulation Of Lipid Binding Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Response To Heat Atrial Cardiac Muscle Cell Development Peroxisome Membrane Biogenesis Protein Import Into Mitochondrial Outer Membrane Regulation Of Reactive Oxygen Species Metabolic Process Protein Import Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Response To Temperature Stimulus Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Protein Kinase Activity Intracellular Receptor Signaling Pathway Protein Import Into Peroxisome Membrane Chaperone-mediated Protein Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Peroxisomal Membrane Transport Regulation Of Kinase Activity Establishment Of Protein Localization To Membrane Bile Acid Secretion Peroxisome Fission Oligopeptide Transport Regulation Of Binding Phagocytosis Positive Regulation Of Protein Import Into Nucleus, Translocation Negative Regulation Of Sodium Ion Transport Renal Absorption Regulation Of Proton Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
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