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RIMS1 and ERC2
Number of citations of the paper that reports this interaction (PMID
12163476
)
44
Data Source:
HPRD
(in vivo, in vitro)
RIMS1
ERC2
Gene Name
regulating synaptic membrane exocytosis 1
ELKS/RAB6-interacting/CAST family member 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Plasma Membrane
Cell Junction
Presynaptic Membrane
Presynaptic Active Zone
Cytoplasm
Cytoskeleton
Cell Junction
Growth Cone
Presynaptic Membrane
Presynaptic Active Zone
Molecular Function
Small GTPase Regulator Activity
Protein Binding
Rab GTPase Binding
Ion Channel Binding
Poly(A) RNA Binding
Metal Ion Binding
Protein Binding
Biological Process
Protein Complex Assembly
Intracellular Protein Transport
Synaptic Transmission
Neurotransmitter Secretion
Visual Perception
Positive Regulation Of Gene Expression
Glutamate Secretion
Synaptic Vesicle Exocytosis
Calcium Ion-dependent Exocytosis
Regulated Secretory Pathway
Secretion
Regulation Of Neurotransmitter Secretion
Regulation Of Long-term Neuronal Synaptic Plasticity
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Regulation Of Catalytic Activity
Response To Stimulus
Membrane Fusion
Positive Regulation Of Inhibitory Postsynaptic Membrane Potential
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
GABA synthesis, release, reuptake and degradation
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Cognitive performance (
20125193
)
Bipolar disorder and schizophrenia (
21057379
)
Hip geometry (
17903296
)
Protein-Protein Interactions
15 interactors:
CACNA1B
CACNA1C
CAMK2A
ERC1
ERC2
RAB10
RAB26
RAB27A
RAB37
RAB3A
SNAP25
STX1A
SYT1
UNC13B
YWHAH
8 interactors:
BSN
MYB
PCLO
PPFIA1
PPFIA2
PPFIA3
PPFIA4
RIMS1
Entrez ID
22999
26059
HPRD ID
09435
10810
Ensembl ID
ENSG00000079841
ENSG00000187672
Uniprot IDs
B7Z7W2
B7Z9Z3
Q3ZCW0
Q86UR5
O15083
PDB IDs
2CSS
Enriched GO Terms of Interacting Partners
?
Vesicle Docking
Membrane Docking
Vesicle Docking Involved In Exocytosis
Secretion By Cell
Exocytosis
Establishment Of Localization In Cell
Secretion
Regulation Of Secretion
Regulation Of Cellular Localization
Regulation Of Exocytosis
Cellular Localization
Glutamate Secretion
Synaptic Transmission
Regulation Of Vesicle-mediated Transport
Vesicle-mediated Transport
Neurotransmitter Secretion
Synaptic Vesicle Transport
Protein Secretion
Synaptic Vesicle Exocytosis
Regulation Of Neurotransmitter Levels
Positive Regulation Of Exocytosis
Rab Protein Signal Transduction
Regulation Of Synaptic Transmission
Acid Secretion
Neurotransmitter Transport
Cell-cell Signaling
Transport
Establishment Of Vesicle Localization
Dicarboxylic Acid Transport
Intracellular Transport
Vesicle Localization
Signaling
Cell Communication
Synaptic Vesicle Docking
Protein Transport
Establishment Of Organelle Localization
Establishment Of Protein Localization
Amino Acid Transport
Regulation Of Synaptic Plasticity
Regulation Of Neurotransmitter Secretion
Organelle Localization
Positive Regulation Of Transport
Ras Protein Signal Transduction
Intracellular Signal Transduction
Protein Localization
Membrane Organization
Intracellular Protein Transport
Regulation Of Membrane Potential
Positive Regulation Of Synaptic Transmission
Membrane Depolarization
Glutamate Secretion
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Neurotransmitter Transport
Acid Secretion
Dicarboxylic Acid Transport
Synaptic Transmission
Amino Acid Transport
Cell-cell Signaling
Secretion By Cell
Secretion
Carboxylic Acid Transport
Organic Acid Transport
Organic Anion Transport
Anion Transport
Ion Transport
Establishment Of Localization In Cell
Cellular Localization
Transport
Synaptic Vesicle Exocytosis
Regulation Of Neuronal Synaptic Plasticity
Signaling
Cell Communication
Synaptic Vesicle Transport
Regulation Of Synaptic Plasticity
Cell-matrix Adhesion
Positive Regulation Of Inhibitory Postsynaptic Membrane Potential
Establishment Of Vesicle Localization
Vesicle Localization
Cell-substrate Adhesion
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Negative Regulation Of Stress Fiber Assembly
Regulation Of Cellular Localization
Negative Regulation Of Actin Filament Bundle Assembly
Positive Regulation Of Histone H3-K9 Methylation
Regulation Of Short-term Neuronal Synaptic Plasticity
Regulation Of Synaptic Transmission
Regulation Of Inhibitory Postsynaptic Membrane Potential
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Establishment Of Organelle Localization
Exocytosis
Positive Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Protein Localization To Plasma Membrane
CAMP-mediated Signaling
Regulation Of Histone H3-K4 Methylation
Organelle Localization
Cellular Response To Interleukin-6
Positive Regulation Of T-helper Cell Differentiation
Cyclic-nucleotide-mediated Signaling
Regulation Of Long-term Neuronal Synaptic Plasticity
Tagcloud
?
abi3bp
angioedema
arachidonic
associations
aua
bicc1
chinese
clusters
col24a1
entity
fbxl7
galnac
genome
han
hlf
hypersensitivity
intolerance
nsaid
nsaids
rad51l
rad51l1
reached
scan
spanish
suffering
suggestive
t13
unrelated
urticaria
Tagcloud (Difference)
?
abi3bp
angioedema
arachidonic
associations
aua
bicc1
chinese
clusters
col24a1
entity
fbxl7
galnac
genome
han
hlf
hypersensitivity
intolerance
nsaid
nsaids
rad51l
rad51l1
reached
scan
spanish
suffering
suggestive
t13
unrelated
urticaria
Tagcloud (Intersection)
?