ERC2 and MYB

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		ERC2	MYB
Gene Name		ELKS/RAB6-interacting/CAST family member 2	v-myb avian myeloblastosis viral oncogene homolog
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Cell Junction Growth Cone Presynaptic Membrane Presynaptic Active Zone	Cytosol Nuclear Matrix
	Molecular Function	Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding WD40-repeat Domain Binding
	Biological Process		G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Calcium Ion Transport Blood Coagulation B Cell Differentiation Positive Regulation Of T-helper Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development Embryonic Digestive Tract Development Homeostasis Of Number Of Cells Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone H3-K9 Methylation Cellular Response To Interleukin-6
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Bipolar disorder and schizophrenia ( 21057379) Hip geometry ( 17903296)	Beta thalassemia/hemoglobin E disease ( 20183929) HbA2 levels ( 23043469) Hematocrit ( 19862010) Hematological and biochemical traits ( 20139978) Hematological parameters ( 19820697) Hematology traits ( 23263863 19853236) Mean corpuscular hemoglobin ( 23263863 20139978 19862010) Mean corpuscular hemoglobin concentration ( 23263863 20139978) Mean corpuscular volume ( 23263863 20139978 19862010) Mean platelet volume ( 22423221) Multiple sclerosis ( 21833088) Obesity-related traits ( 23251661) Other erythrocyte phenotypes ( 19862010) Platelet counts ( 22139419 20139978) Red blood cell count ( 20139978) Red blood cell traits ( 20927387) White blood cell count ( 20139978) White blood cell types ( 21738478)
Protein-Protein Interactions		8 interactors: BSN MYB PCLO PPFIA1 PPFIA2 PPFIA3 PPFIA4 RIMS1	43 interactors: BTRC CCND3 CEBPB CEBPE CHD3 CREBBP CSNK2A1 EP300 ERC2 FBXW2 FBXW5 FBXW7 HIPK2 HLF KAT2A MAF MAPK1 MYBBP1A MYOZ2 NCL NCOR1 NLK PAX5 PIAS1 PML PPM1K RBX1 RPL4 RQCD1 SIN3A SKI SKP2 SMARCA2 SND1 SP100 SUMO1 SUMO2 TRIM28 TTF2 UBE2I UPF2 ZFHX3 ZMYND11
Entrez ID		26059	4602
HPRD ID		10810	01810
Ensembl ID		ENSG00000187672	ENSG00000118513
Uniprot IDs		O15083	P10242 Q14025 Q708E1 Q708E9
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Neurotransmitter Transport Acid Secretion Dicarboxylic Acid Transport Synaptic Transmission Amino Acid Transport Cell-cell Signaling Secretion By Cell Secretion Carboxylic Acid Transport Organic Acid Transport Organic Anion Transport Anion Transport Ion Transport Establishment Of Localization In Cell Cellular Localization Transport Synaptic Vesicle Exocytosis Regulation Of Neuronal Synaptic Plasticity Signaling Cell Communication Synaptic Vesicle Transport Regulation Of Synaptic Plasticity Cell-matrix Adhesion Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Establishment Of Vesicle Localization Vesicle Localization Cell-substrate Adhesion Calcium Ion-dependent Exocytosis Of Neurotransmitter Negative Regulation Of Stress Fiber Assembly Regulation Of Cellular Localization Negative Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Histone H3-K9 Methylation Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of Synaptic Transmission Regulation Of Inhibitory Postsynaptic Membrane Potential Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Establishment Of Organelle Localization Exocytosis Positive Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Localization To Plasma Membrane CAMP-mediated Signaling Regulation Of Histone H3-K4 Methylation Organelle Localization Cellular Response To Interleukin-6 Positive Regulation Of T-helper Cell Differentiation Cyclic-nucleotide-mediated Signaling Regulation Of Long-term Neuronal Synaptic Plasticity	RNA Biosynthetic Process Negative Regulation Of Gene Expression Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Viral Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Protein Sumoylation Cellular Protein Modification Process Rhythmic Process Protein Modification By Small Protein Conjugation Developmental Process Peptidyl-lysine Modification PML Body Organization Cell Cycle Regulation Of Signal Transduction Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process
Tagcloud ?			amphibian amphibians assume definitive deoxynucleotidyl ectotherms elasmobranchs elegant extraembryonic gata gnathostomes grafting hematopoiesis icm ikaros intraembryonic lck leydig lymphopoiesis mesoderm myeloblastosis oellacher primitive rag spiral tdt teleosts thymopoietic undeniably vertebrates
Tagcloud (Difference) ?			amphibian amphibians assume definitive deoxynucleotidyl ectotherms elasmobranchs elegant extraembryonic gata gnathostomes grafting hematopoiesis icm ikaros intraembryonic lck leydig lymphopoiesis mesoderm myeloblastosis oellacher primitive rag spiral tdt teleosts thymopoietic undeniably vertebrates
Tagcloud (Intersection) ?